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Consortium for Imaging and Biomarkers (CIB)

The Consortium for Imaging and Biomarkers (CIB) seeks to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and cancer diagnosis by integrating imaging strategies with biomarkers into complementary approaches.

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About the Consortium for Imaging and Biomarkers

The Consortium for Imaging and Biomarkers aims to integrate imaging strategies and biomarker methodologies into a singular complementary approach to cancer detection. Investigators Work in multi-disciplinary teams to perform collaborative studies, exchange information, share knowledge and leverage common resources.

Overdiagnosis (finding cancers that will never affect a person’s health) and false positives (test results that show cancer when none is there) present significant clinical problems in the prevention, detection and treatment of cancer. There is a need to more accurately identify early-stage aggressive cancers and distinguish lesions that are life threatening from those that are not.

The Consortium for imaging and Biomarkers Research Units develop, optimize, and clinically validate novel methods to:

  • Detect aggressive cancers at the earliest stages possible;
  • Reduce overdiagnosis;
  • Reduce false positive tests; and
  • Identify lethal cancers from non-lethal disease.

The goal of the Consortium for imaging and Biomarkers is to develop improved methods for the early detection of aggressive cancer by managing overdiagnosis, reducing false positives and identifying lethal cancers from non-lethal disease using strategies aimed at effective integration and validation of imaging and biomarkers.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Giles, Erin

University Of Michigan At Ann Arbor
United States

Obesity, body fat distribution, and breast cancer risk: is visceral fat the culprit after menopause? 5R01CA269726-02 Marjorie Perloff, M.D.
Gill, Brian John Andrew

Columbia University Health Sciences
United States

The Impact of Local and Reversible Change to GABAergic Inhibitory Signaling on Tumor-Induced Cortical Dysfunction in Glioma 1R01NS140658-01A1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Gill, Brian John Andrew

Columbia University Health Sciences
United States

The Impact of Local and Reversible Change to GABAergic Inhibitory Signaling on Tumor-Induced Cortical Dysfunction in Glioma 1R01NS140658-01A1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Godwin, Andrew K.

University Of Kansas Medical Center
United States

Extracellular Vesicle Proteomic Fingerprinting of Ovarian Cancer for Early Detection with a Nanoengineered Microsystem 5R01CA260132-05 Matthew Young, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

5mC and 5hmC DNA alterations as sensitive and specific biomarkers for the non-invasive early detection of pancreatic ductal adenocarcinoma 1U01CA296639-01A1 Claire Zhu, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

Exosome-based microRNA biomarkers for Non-invasive and Early Detection of Pancreatic Cancer 3U01CA214254-08S2 Matthew Young, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

Exosomal biomarkers for the early detection of hepatocellular carcinoma 5R01CA271443-03 Matthew Young, Ph.D.
Goggins, Michael G.

Johns Hopkins University
United States

Using markers to improve pancreatic cancer screening and surveillance: a multi-center study 5U01CA210170-09 Matthew Young, Ph.D.
Goncalves, Marcus Dasilva

New York University School Of Medicine
United States

Molecular Mechanisms of Fructose-induced Colorectal Cancer Cell Survival 5R01CA258697-05 Amit Kumar, Ph.D.
Gonzalez, Brian D

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Impact of Targeted Therapy on Cancer-Related Cognitive Impairment 5R01CA287666-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Gonzalez, Brian D

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Impact of Targeted Therapy on Cancer-Related Cognitive Impairment 5R01CA287666-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Goode, Diana J

University Of New England
United States

Novel expression of MHC class II on DRG neurons and its role in promoting antinociceptive CD4+ T cells in females during chemotherapy-induced peripheral neuropathy 5R01CA267554-04 Rachel Altshuler, Ph.D.
Goode, Diana J

University Of New England
United States

Novel expression of MHC class II on DRG neurons and its role in promoting antinociceptive CD4+ T cells in females during chemotherapy-induced peripheral neuropathy 5R01CA267554-04 Rachel Altshuler, Ph.D.
Grady, William Mallory

Fred Hutchinson Cancer Center
United States

Biomarkers for optimizing risk prediction and early detection of cancers of the colon and esophagus 5U2CCA271902-04 Matthew Young, Ph.D.
Grady, William Mallory

Fred Hutchinson Cancer Center
United States

Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiome 3U54CA274374-04S2 Christos Patriotis, Ph.D., M.Sc.

Program Contact(s)

Sudhir Srivastava, Ph.D., M.P.H.
Email: sudhir.srivastava@nih.gov

Guillermo Marquez, Ph.D.
Email: guillermo.marquez@nih.gov