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Chemopreventive Agent Development

Designs, develops, implements, and monitors research on interventions that may block, reverse, or delay the early stages of cancer. Investigates nutrients, micronutrients, natural products, pharmacologic agents, biomolecules, and vaccines from preclinical to early-phase I clinical studies. Helps investigators to bridge the gaps between biology and identifying potential targets, and between discovery of targets and agents and clinical testing in people.

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Major Programs

Staff List

Photo Name, Email, Phone Room Group(s)/Office
Asefa, Wosene
 wosene.asefa@nih.gov
240-276-6422 		5E504 Program Support Assistant | Chemopreventive Agent Development
Biswas, Kajal, Ph.D.
 kajal.biswas2@nih.gov
240-276-5614 		5E540 Program Officer | Chemopreventive Agent Development
Cholewa, Brian, Ph.D.
 brian.cholewa@nih.gov
240-276-7545 		5E446 Deputy Chief | Chemopreventive Agent Development
Clifford, John, Ph.D.
 john.clifford@nih.gov
202-235-4482 		5E430 Program Officer | Chemopreventive Agent Development
Gunasekharan, Vignesh, Ph.D.
 vignesh.gunasekharan@nih.gov
240-276-5814 		5E438 Program Officer | Chemopreventive Agent Development
Mohammed, Altaf, Ph.D.
 altaf.mohammed@nih.gov
240-276-6082 		5E542 Deputy Chief | Chemopreventive Agent Development
Nalli, Ancy, Ph.D., M.S.
 ancy.nalli@nih.gov
202-276-5265 		5E536 Program Officer | Chemopreventive Agent Development
Sei, Shizuko, M.D.
 shizuko.sei@nih.gov
240-276-5005 		5E452 Co-Chief | Chemopreventive Agent Development
Shoemaker, Robert, Ph.D.
 robert.shoemaker@nih.gov
240-276-7077 		5E454 Co-Chief | Chemopreventive Agent Development
Acting Chief | Nutritional Science
Vlad, Anda, M.D., Ph.D.
 anda.vlad@nih.gov
240-276-6422 		5E538 Program Officer | Chemopreventive Agent Development

Grants

PI Name PI Organization Title Grant Number Program Official
Gill, Brian John Andrew

Columbia University Health Sciences
United States

 The Impact of Local and Reversible Change to GABAergic Inhibitory Signaling on Tumor-Induced Cortical Dysfunction in Glioma 1R01NS140658-01A1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Godwin, Andrew K.

University Of Kansas Medical Center
United States

 Extracellular Vesicle Proteomic Fingerprinting of Ovarian Cancer for Early Detection with a Nanoengineered Microsystem 5R01CA260132-05 Matthew Young, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

 Exosomal biomarkers for the early detection of hepatocellular carcinoma 5R01CA271443-03 Matthew Young, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

 Exosome-based microRNA biomarkers for Non-invasive and Early Detection of Pancreatic Cancer 3U01CA214254-08S2 Matthew Young, Ph.D.
Goel, Ajay

Beckman Research Institute/City Of Hope
United States

 5mC and 5hmC DNA alterations as sensitive and specific biomarkers for the non-invasive early detection of pancreatic ductal adenocarcinoma 1U01CA296639-01A1 Claire Zhu, Ph.D.
Goggins, Michael G.

Johns Hopkins University
United States

 Using markers to improve pancreatic cancer screening and surveillance: a multi-center study 5U01CA210170-09 Matthew Young, Ph.D.
Goncalves, Marcus Dasilva

New York University School Of Medicine
United States

 Molecular Mechanisms of Fructose-induced Colorectal Cancer Cell Survival 5R01CA258697-05 Amit Kumar, Ph.D.
Gonzalez, Brian D

H. Lee Moffitt Cancer Ctr & Res Inst
United States

 Impact of Targeted Therapy on Cancer-Related Cognitive Impairment 5R01CA287666-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Goode, Diana J

University Of New England
United States

 Novel expression of MHC class II on DRG neurons and its role in promoting antinociceptive CD4+ T cells in females during chemotherapy-induced peripheral neuropathy 5R01CA267554-04 Rachel Altshuler, Ph.D.
Grady, William Mallory

Fred Hutchinson Cancer Center
United States

 Biomarkers for optimizing risk prediction and early detection of cancers of the colon and esophagus 5U2CCA271902-04 Matthew Young, Ph.D.
Grady, William Mallory

Fred Hutchinson Cancer Center
United States

 Understanding adenoma progression: Interplay among tissue microenvironment, clonal architecture, and gut microbiome 3U54CA274374-04S2 Christos Patriotis, Ph.D., M.Sc.
Greene, Nicholas Perry

University Of Arkansas At Fayetteville
United States

 DEVELOPMENT OF TARGETED APPROACHES IN PREVENTION OF CANCER-CACHEXIA 5R01AR075794-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Grimm, Lars J

Duke University
United States

 Dynamic imaging and tissue biomarker models to delineate indolent from aggressive breast calcifications 4R01CA271237-04 Guillermo Marquez, Ph.D.
Grogan, Eric L

Vanderbilt University Medical Center
United States

 Clinical Utility of Biomarkers Driven Management of Indeterminate Pulmonary Nodules 5R01CA252964-05 Claire Zhu, Ph.D.
Groninger, J. Hunter

Medstar Health Research Institute
United States

 Cognitive behavioral theory-assisted virtual reality for chronic cancer pain (VR-CAN): device prototype development and feasibility testing 1R21CA299799-01 Brennan Streck, Ph.D., RN, M.P.H.