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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Chung, Michael Hoonbae

Emory University
United States

HIV/cervical cancer cOntrol and Prevention clinical sitE in Kenya (HOPE-Kenya) 3UG1CA275400-04S1 Maria Silvina Frech, Ph.D., M.S.
Chung, Ki Young

Prisma Health - Upstate
United States

NCORP of the Carolinas (Greenville Health System NCORP) 3UG1CA189972-11S1 Vanessa A. White, M.P.H.
Chung, Ki Young

Prisma Health - Upstate
United States

NCORP of the Carolinas (Greenville Health System NCORP) 3UG1CA189972-11S1 Vanessa A. White, M.P.H.
Clapper, Margie L.

Research Inst Of Fox Chase Can Ctr
United States

Folic Acid Supplementation and Colitis-associated Colon Carcinogenesis 5R01CA262551-04 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Clapper, Margie L.

Research Inst Of Fox Chase Can Ctr
United States

Cancer Prevention-Interception Targeted Agent Discovery Program at Fox Chase Cancer Center 5U54CA272686-04
Clare, Susan E.

Northwestern University At Chicago
United States

Lipid-initiated epigenetic reprogramming of the breast to a neural phenotype 1R21CA288676-01A1
Cocucci, Emanuele

Ohio State University
United States

A SYNTHETIC BIOMARKER TO UNIVERSALLY ASSESS THE RELATIVE CONTRIBUTION OF HEATHY AND CANCEROUS TISSUE TO CIRCULATING EV POOL 5R01CA270251-03 Matthew Young, Ph.D.
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Cohn, Barbara A

Public Health Institute
United States

Discriminatory Mechanisms in Early-Onset and Lethal Prostate Cancer 5R01CA264519-05 Howard L. Parnes, M.D.
Cook, Linda S

University Of Colorado Denver
United States

NOT-CA-24-111 Improving Strategies for Cancer Reduction through Early-detection and ENgagement (I-SCREEN) 3UG1CA286941-02S1 Elyse LeeVan, M.D., M.P.H.
Cremer, Miriam

Cleveland Clinic Lerner Com-Cwru
United States

Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (SCALE) 5R01CA266059-04 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Curtis, Amarinthia E

Spartanburg Regional Medical Center
United States

Upstate Carolina Consortium - Community Oncology Research Program 3UG1CA239762-06S1 Vanessa A. White, M.P.H.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia Laboratory Biomarker Analysis, Simplified Patient Care Strategy ECOG-ACRIN Cancer Research Group Active, not recruiting
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment Children's Oncology Group Recruiting
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer Conization, Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Conventional Surgery, Therapeutic Lymphadenectomy GOG Foundation Active, not recruiting
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study Non-Interventional Study Wake Forest University Health Sciences Not yet recruiting
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Telephone Support in Advanced Gastrointestinal Cancer Acceptance and Commitment Therapy, Education/Support Indiana University Recruiting
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Survey Administration, Whole-Brain Radiotherapy NRG Oncology Recruiting
Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial Laser Therapy, Quality of Life Assessment, Questionnaire Administration, Sham Intervention Alliance for Clinical Trials in Oncology Not yet recruiting
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy, Intensity-Modulated Radiation Therapy, Magnetic Resonance Imaging, MnSOD Mimetic BMX-001, Placebo Administration, Questionnaire Administration NRG Oncology Recruiting