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Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Etiology and Early Marker Studies (EEMS)

The Etiology and Early Marker Studies (EEMS) is a component of the PLCO Trial. By collecting biologic materials and risk factor information from trial participants before the diagnosis of disease, PLCO EEMS adds substantial value to the trial, providing a resource for cancer research, focused, in particular, on cancer etiology and early markers.

Etiologic studies investigate the environmental, biochemical and genetic risk factors for cancer. Early detection studies aim to develop reproducible, diagnostics-ready biomarkers of early disease.

Data and biospecimens currently available for research in EEMS include:

PLCO data and biospecimens are available to all qualified researchers through a peer-review process. The EEMS program accepts proposals for access to PLCO biospecimens twice a year in June and December. Details of the review process and application materials are available on https://cdas.cancer.gov.