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Consortium for Imaging and Biomarkers (CIB)

The Consortium for Imaging and Biomarkers (CIB) seeks to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and cancer diagnosis by integrating imaging strategies with biomarkers into complementary approaches.

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About the Consortium for Imaging and Biomarkers

The Consortium for Imaging and Biomarkers aims to integrate imaging strategies and biomarker methodologies into a singular complementary approach to cancer detection. Investigators Work in multi-disciplinary teams to perform collaborative studies, exchange information, share knowledge and leverage common resources.

Overdiagnosis (finding cancers that will never affect a person’s health) and false positives (test results that show cancer when none is there) present significant clinical problems in the prevention, detection and treatment of cancer. There is a need to more accurately identify early-stage aggressive cancers and distinguish lesions that are life threatening from those that are not.

The Consortium for imaging and Biomarkers Research Units develop, optimize, and clinically validate novel methods to:

  • Detect aggressive cancers at the earliest stages possible;
  • Reduce overdiagnosis;
  • Reduce false positive tests; and
  • Identify lethal cancers from non-lethal disease.

The goal of the Consortium for imaging and Biomarkers is to develop improved methods for the early detection of aggressive cancer by managing overdiagnosis, reducing false positives and identifying lethal cancers from non-lethal disease using strategies aimed at effective integration and validation of imaging and biomarkers.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Mugo, Nelly Rwamba

Kenya Medical Research Institute (Kemri)
United States

KEMRI-PHRD UG1 CASCADE NETWORK UNIT: CERVICAL CANCER PREVENTION FOR WOMEN LIVING WITH HIV RESEARCH 3UG1CA285132-03S1 Maria Silvina Frech, Ph.D., M.S.
Muller, Carolyn Y

University Of New Mexico Health Scis Ctr
United States

The NCI Community Oncology Research Program: The New Mexico NCORP 3UG1CA189856-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Muller, Carolyn Y

University Of New Mexico Health Scis Ctr
United States

The NCI Community Oncology Research Program: The New Mexico NCORP 3UG1CA189856-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Mungo, Chemtai

Univ Of North Carolina Chapel Hill
United States

Feasibility of artesunate to improve HPV and cervical precancer treatment outcomes among HIV positive women in LMICs 3R34CA284983-03S2 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Mungo, Chemtai

Univ Of North Carolina Chapel Hill
United States

Expanded Safety and Preliminary Efficacy of Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in Women with HIV in Africa 3R37CA306827-01S2 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Murenzi, Gad

Research For Development
United States

Rwanda CASCADE Clinical Trials Site for cervical cancer prevention 5UG1CA284908-03 Maria Silvina Frech, Ph.D., M.S.
Mustian, Karen M.

University Of Rochester
United States

URCC NCORP Research Base 3UG1CA189961-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Mustian, Karen M.

University Of Rochester
United States

URCC NCORP Research Base 3UG1CA189961-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Muzumdar, Mandar Deepak

Yale University
United States

Targeting pancreatic endocrine-exocrine signaling in cancer development with incretin mimetics 1R01CA296916-01
Mwesigwa, Betty

Makerere University Walter Reed Project
United States

Implementing HIV/Cervical Cancer Prevention CASCADE Clinical Trials in Uganda (CASCADE UGANDA) 5UG1CA275412-04 Maria Silvina Frech, Ph.D., M.S.
Nabavi, Sheida

University Of Connecticut Storrs
United States

SCH: Robust Multimodal Longitudinal AI for Enhanced Breast Cancer Screening 5R01CA297855-02 Claire Zhu, Ph.D.
Naicker, Nivashnee

Centre/Aids Programme/Res/South Africa
United States

CAPRISA CASCADE Clinical Trials Network Clinical Research Site 5UG1CA284671-03 Maria Silvina Frech, Ph.D., M.S.
Nappi, Lucia

Provincial Health Services Authority
United States

Integrating investigational miR371a-3p with conventional radiology imaging for earlier and more precise detection of active germ cell malignancy: A BCC/SWOG/S1823 secondary use of data collaboration. 5R37CA264798-03 Guillermo Marquez, Ph.D.
Nath, Kavindra

University Of Pennsylvania
United States

Metabolic Biomarkers of Response of Mantle Cell Lymphoma to Bruton Tyrosine Kinase Inhibition 5R01CA228457-05 Nicholas Hodges, Ph.D.
Nelson, Randy J.

West Virginia University
United States

Mechanism Underlying Sleep Disruption by Mammary Tumors 5R21CA276027-02 Marjorie Perloff, M.D.

Program Contact(s)

Sudhir Srivastava, Ph.D., M.P.H.
Email: sudhir.srivastava@nih.gov

Guillermo Marquez, Ph.D.
Email: guillermo.marquez@nih.gov