Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Clinical Trials

Title	Intervention	Sponsor	Status
A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial	Electronic Health Record Review, Interview, Support, Survey Administration	Fred Hutchinson Cancer Center	Not yet recruiting
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula	Biospecimen Collection, Distal Pancreatectomy, Lanreotide, Questionnaire Administration, Saline	SWOG Cancer Research Network	Recruiting
Communication About Sexual Health in Gynecologic Cancer	Sexual Health Resources, Starting the Conversation	Fox Chase Cancer Center	Recruiting
Mosaic Trial for Stem Cell Transplant Recipients	Enhanced Usual Care (Control) Website, Intervention website	Northwestern University	Recruiting
The MIND-BC Study: MIND Diet for Breast Cancer Cognition	MIND Diet, Usual Diet	H. Lee Moffitt Cancer Center and Research Institute	Recruiting
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia	Best Practice, Biospecimen Collection, Cytarabine, Electronic Health Record Review, Placebo Administration, Xylitol-containing Oral Wipe	Children's Oncology Group	Not yet recruiting
Distance-Based Exercise to Preserve Function and Prevent Disability	Accelerometry, Aerobic Exercise Intervention, Dumbbell Exercise Intervention, Electronic Health Record Review, Exercise intervention, Interview, Questionnaire Administration, Telemedicine	Alliance for Clinical Trials in Oncology	Not yet recruiting
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study	Non-Interventional Study	Wake Forest University Health Sciences	Recruiting
Understanding Needs of Older Patients Prior to Starting Cancer Treatment	Assessment, Educational Intervention, Electronic Health Record Review, Internet-Based Intervention, Interview, Survey Administration	Wake Forest University Health Sciences	Enrolling by invitation