| Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome |
Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5, Biopsy, Biospecimen Collection, Colonoscopy, Nogapendekin Alfa, Placebo Administration, Questionnaire Administration |
Not yet recruiting |
| Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast |
Afimoxifene, Laboratory Biomarker Analysis, Placebo, Tamoxifen Citrate |
Recruiting |
| Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis |
Atorvastatin Calcium, Biospecimen Collection, Placebo Administration, Biopsy of Colon, Questionnaire Administration |
Recruiting |
| Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors |
Best Practice, Dietary Intervention, Message, Quality-of-Life Assessment, Questionnaire Administration |
Active, not recruiting |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability |
Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Whole-Brain Radiotherapy |
Recruiting |
| Testing Obeticholic Acid for Familial Adenomatous Polyposis |
Biopsy, Obeticholic Acid, Placebo Administration, Biospecimen Collection, Gastrointestinal Endoscopy, Questionnaire Administration |
Recruiting |
| Testing Ramipril to Prevent Memory Loss in People With Glioblastoma |
Ramipril |
Recruiting |
| Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy |
Best Practice, Wound Dressing Material, Quality-of-Life Assessment, Questionnaire Administration |
Recruiting |
| Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers |
Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration |
Recruiting |
| Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy |
Exercise Intervention |
Recruiting |
| Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland |
Apalutamide, Quality-of-Life Assessment, Biospecimen Collection |
Recruiting |
| Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer |
Pembrolizumab, Pemetrexed, Carboplatin, Comprehensive Geriatric Assessment, Questionnaire Administration, Quality-of-Life Assessment |
Recruiting |
| Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer |
Oxybutynin Chloride, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration |
Recruiting |
| The National Myelodysplastic Syndromes (MDS) Study |
Therapeutic |
Recruiting |
| The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial) |
Placebo, Sulindac 400 MG |
Recruiting |
| To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring |
Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration, Sinecatechins |
Recruiting |
| Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer |
Solaraze and Vaniqa |
Recruiting |
| Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia |
Imiquimod, Topical Fluorouracil |
Active, not recruiting |
| TrAstuzumab Cardiomyopathy Therapeutic Intervention With Carvedilol |
Carvedilol |
Recruiting |
| Treating Pain in Children With Cancer: Pain Buddy |
Pain Buddy |
Recruiting |