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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Deng, Youping

University Of Hawaii At Manoa
United States

Circulating lipid and miRNA markers for early detection of breast cancer among women with abnormal mammograms 5R01CA230514-05 Christos Patriotis, Ph.D., M.Sc.
Dhakal, Soma

Virginia Commonwealth University
United States

Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers 5R61CA278445-03 Christos Patriotis, Ph.D., M.Sc.
Diaz, Juan Sebastian Gomez

University Of California At Davis
United States

A miniaturized neural network enabled nanoplasmonic spectroscopy platform for label-free cancer detection in biofluids 3R01CA273253-03S1 Nicholas Hodges, Ph.D.
Dickinson, Sally E

University Of Arizona
United States

Investigating novel targets for topical immunoprevention of keratinocytic skin cancer 1UG3CA290443-01A1 Altaf Mohammed, Ph.D.
Digirolamo, Gregory James

Univ Of Massachusetts Med Sch Worcester
United States

Increasing Nodule Detection in Lung Cancer by Non-Conscious Detection of "Missed" Nodules and Machine Learning 5R01CA269903-04
Doescher, Mark P

University Of Oklahoma Hlth Sciences Ctr
United States

Oklahoma Tribal, Rural, Urban Cancer Screening Trial ACCESS Hub 3UG1CA287044-02S1 Elyse LeeVan, M.D., M.P.H.
Doolittle, Gary C.

University Of Kansas Medical Center
United States

The University of Kansas Cancer Center's- MCA Rural NCORP- extension 3UG1CA239767-06S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Doolittle, Gary C.

University Of Kansas Medical Center
United States

The University of Kansas Cancer Center's- MCA Rural NCORP- extension 3UG1CA239767-06S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Drake, Richard R.

Medical University Of South Carolina
United States

Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids 5R33CA267226-03
Drescher, Charles

Swedish Medical Center, First Hill
United States

The Pacific Cancer Research Consortium (PCRC), an NCORP Community Site 3UG1CA189953-11S1 Vanessa A. White, M.P.H.
Drescher, Charles

Swedish Medical Center, First Hill
United States

The Pacific Cancer Research Consortium (PCRC), an NCORP Community Site 3UG1CA189953-11S1 Vanessa A. White, M.P.H.
Dryden-Peterson, Scott

Brigham And Women'S Hospital
United States

Botswana CASCADE Clinical Trials Site 3UG1CA275416-04S1 Maria Silvina Frech, Ph.D., M.S.
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices Non-Interventional Wake Forest University Health Sciences Enrolling by invitation
Understanding Needs of Older Patients Prior to Starting Cancer Treatment Assessment, Educational Intervention, Electronic Health Record Review, Internet-Based Intervention, Interview, Survey Administration Wake Forest University Health Sciences Enrolling by invitation
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer Best Practice, Informational Intervention, Informational Intervention with Coaching, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer Behavioral Intervention, Educational Intervention, Internet-Based Intervention, Interview, Survey Administration, Virtual Technology Intervention City of Hope Medical Center Not yet recruiting
Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer Educational Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis, Medical Device Usage and Evaluation, Quality-of-Life Assessment, Questionnaire Administration Children's Oncology Group Active, not recruiting
Wellness App for Sleep Disturbance in Hematological Cancer Patients Wellness app intervention #1, Wellness app intervention #2 The University of Texas Health Science Center at San Antonio Recruiting
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer Intensity-Modulated Radiation Therapy, Three-Dimensional Conformal Radiation Therapy NRG Oncology Active, not recruiting
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia Best Practice, Biospecimen Collection, Cytarabine, Electronic Health Record Review, Placebo Administration, Xylitol-containing Oral Wipe Children's Oncology Group Not yet recruiting