Skip to main content
An official website of the United States government

Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name PI Organization Title Grant Number Program Official
Schoen, Robert E.

University Of Pittsburgh At Pittsburgh
United States

 Blood-Based Testing for Advanced Adenoma 5U01CA271884-04 Matthew Young, Ph.D.
Schroeck, Florian R

Veterans Education/Res/Assn/North/Ne
United States

 Replacing Invasive Cystoscopy with Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance 5R37CA275916-03 Claire Zhu, Ph.D.
Schuetze, Scott Michael

University Of Michigan At Ann Arbor
United States

 Early Phase Clinical Cancer Prevention Consortium 2UG1CA242632-06 Donald Johnsey
Sears, Rosalie C

Oregon Health & Science University
United States

 An atlas of pancreatic tumorigenesis in the context of altered DNA repair occurring in high-risk individuals 4U01CA294548-02 Indu Kohaar, Ph.D., M.Phil., M.Sc.
Sears, Rosalie C

Oregon Health & Science University
United States

 Validation of novel imaging and molecular tests for early detection of pancreatic cancer through risk-stratified community engagement programs 5U01CA278923-03 Matthew Young, Ph.D.
Sedrak, Mina S

University Of California Los Angeles
United States

 Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline 5R01CA280088-03 Goli Samimi, Ph.D., M.P.H.
Sedrak, Mina S

University Of California Los Angeles
United States

 Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline 5R01CA280088-03 Goli Samimi, Ph.D., M.P.H.
Sedrak, Mina S

University Of California Los Angeles
United States

 Using Senolytics to Improve Physical Function in Older Breast Cancer Survivors 5R21CA277660-03 Goli Samimi, Ph.D., M.P.H.
Sedrak, Mina S

University Of California Los Angeles
United States

 Using Senolytics to Improve Physical Function in Older Breast Cancer Survivors 5R21CA277660-03 Goli Samimi, Ph.D., M.P.H.
Segal, Leopoldo Nicolas

New York University School Of Medicine
United States

 Microbial and host biomarker development for detection and prognosis of early stage non-small cell lung cancer 5U2CCA271890-03 Guillermo Marquez, Ph.D.
Segata, Nicola

University Of Trento
United States

 PROSPECT - Microbiome Studies. (PATHWAYS, RISK FACTORS, AND MOLECULES TO PREVENT EARLY-ONSET COLORECTAL TUMOURS) 1OT2CA297205-01 Asad Umar, D.V.M., Ph.D.
Seguin-Fowler, Rebecca Anne

Texas A&M Agrilife Research
United States

 Deep in the Heart for Women: A Community-Engaged Intervention Study to Catalyze a Culture of Health in Rural South Texas 1R01HL179449-01 Goli Samimi, Ph.D., M.P.H.
Semmes, Oliver John

Old Dominion University
United States

 Virginia-UCLA-Toronto Biomarker Characterization Center 5U2CCA271894-05 Indu Kohaar, Ph.D., M.Phil., M.Sc.
Sempere, Lorenzo

Michigan State University
United States

 Image-Guided Intraductal Ablative Procedure for Primary Prevention of Breast Cancer 5R01CA258314-04 Edward Sauter, M.D., Ph.D.
Sen, Subrata

University Of Tx Md Anderson Can Ctr
United States

 Circulating Biomarkers and Imaging for Early Detection of Pancreatic Cancer 5U01CA214263-07 Matthew Young, Ph.D.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554