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Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

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About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Reese, Jennifer Barsky

Research Inst Of Fox Chase Can Ctr
United States

Promoting Effective Clinical Communication about Sexual Health after Gynecologic Cancer: A Randomized Controlled Trial of a Patient-Focused Intervention 5R01CA285674-02 Vanessa A. White, M.P.H.
Remick, Scot C

Mainehealth
United States

MaineHealth Cancer Care Network (MHCCN) and NCORP Activities across the Lifespan 3UG1CA239771-06S1 Vanessa A. White, M.P.H.
Remick, Scot C

Mainehealth
United States

MaineHealth Cancer Care Network (MHCCN) and NCORP Activities across the Lifespan 3UG1CA239771-06S1 Vanessa A. White, M.P.H.
Reuland, Daniel S.

Univ Of North Carolina Chapel Hill
United States

Administrative Supplement: CSRN Vanguard Study 3UG1CA286949-02S1 Elyse LeeVan, M.D., M.P.H.
Richards-Kortum, Rebecca R.

Rice University
United States

Sample-to-answer HPV DNA nucleic acid test for cervical cancer screening in Mozambique 3U01CA292741-02S1 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Richards-Kortum, Rebecca R.

Rice University
United States

Low-cost mobile colposcopy and confocal imaging for global prevention of cervical cancer 5R01CA251911-05 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Mosaic: RCT of a Digital Health Intervention Delivering Peer Support Narratives and Psychoeducation to English- and Spanish-Speaking Stem Cell Transplant Recipients 5R01CA292116-02 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Mosaic: RCT of a Digital Health Intervention Delivering Peer Support Narratives and Psychoeducation to English- and Spanish-Speaking Stem Cell Transplant Recipients 5R01CA292116-02 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial 5R01CA271220-04 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial 5R01CA271220-04 Brennan Streck, Ph.D., RN, M.P.H.
Robbins, Hilary A.

International Agency For Res On Cancer
United States

The Lung EArly Proteins project: A LEAP toward implementing biomarkers in lung cancer screening 4R01CA262164-04 Claire Zhu, Ph.D.
Robertson, Gavin P.

Pennsylvania State Univ Hershey Med Ctr
United States

Targeting Aldehyde Dehydrogenase for Cancer Prevention 5R01CA241148-05
Robertson, Sarah E

Dartmouth College
United States

Learning about the effectiveness of lung cancer screening in real-world target populations 4R00CA287059-03 Neeraj Saxena, Ph.D.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554