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Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

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About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Milanovich, Samuel J.

Sanford Research/Usd
United States

Sanford Community Cancer Program of the North Central Plains (NCORP) 3UG1CA189825-11S1 Vanessa A. White, M.P.H.
Milbury, Kathrin

University Of Tx Md Anderson Can Ctr
United States

Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers 4R37CA231522-07 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Milbury, Kathrin

University Of Tx Md Anderson Can Ctr
United States

Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers 4R37CA231522-07 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Milbury, Kathrin

University Of Tx Md Anderson Can Ctr
United States

Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family Caregivers 4R37CA231522-07 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Miyano, Masaru

Beckman Research Institute/City Of Hope
United States

Evaluating the ELF5 Clock as a Biomarker in Breast Cancer Prevention Trials 1R03CA300614-01 Sidney Fu, M.D.
Morilak, David A

University Of Texas Hlth Science Center
United States

Therapy-induced cognitive impairment in a rat model of prostate cancer 5R01CA285183-03 John Clifford, Ph.D.
Morilak, David A

University Of Texas Hlth Science Center
United States

Therapy-induced cognitive impairment in a rat model of prostate cancer 5R01CA285183-03 John Clifford, Ph.D.
Morin, Olivier

University Of California, San Francisco
United States

Development of a Personalized Voxel-wise Prediction of Brain Metastases using Multi-Parametric MR Imaging to Reduce Treatment Toxicity 1R01CA292043-01A1 Marjorie Perloff, M.D.
Morin, Olivier

University Of California, San Francisco
United States

Development of a Personalized Voxel-wise Prediction of Brain Metastases using Multi-Parametric MR Imaging to Reduce Treatment Toxicity 1R01CA292043-01A1 Marjorie Perloff, M.D.
Moscicki, Anna-Barbara

University Of California Los Angeles
United States

Real-world effectiveness of HPV vaccine in women living with HIV and its impact on cervical cancer screening accuracies 5R01CA281293-03 Maria Silvina Frech, Ph.D., M.S.
Moses, John Edward

Cold Spring Harbor Laboratory
United States

Discovery of Natural Products and Natural Product Derivatives as Inhibitors of KLK6 to Prevent the Progression of Preneoplastic Ductal Pancreatic Cancer 1UG3CA290364-01A1 Altaf Mohammed, Ph.D.
Mosher, Catherine E

Indiana University Indianapolis
United States

Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal Cancer 5R01CA289486-02
Mosher, Catherine E

Indiana University Indianapolis
United States

Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal Cancer 5R01CA289486-02
Mosher, Catherine E

Indiana University Indianapolis
United States

Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal Cancer 5R01CA289486-02
Mu, Ping

Yale University
United States

Unveiling the Role of UBE2J1 as the E2 Ubiquitin Conjugating Enzyme in Androgen Receptor Degradation 5R01CA292949-03 Indu Kohaar, Ph.D., M.Phil., M.Sc.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554