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Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

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About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Marker, Ryan J

University Of Colorado Denver
United States

Effects of a telehealth exercise program for rural cancer survivors with cancer-related fatigue including integrated longitudinal assessments of objective physical function and fatty acid oxidation 5R01CA292482-02 Goli Samimi, Ph.D., M.P.H.
Marker, Ryan J

University Of Colorado Denver
United States

Effects of a telehealth exercise program for rural cancer survivors with cancer-related fatigue including integrated longitudinal assessments of objective physical function and fatty acid oxidation 5R01CA292482-02 Goli Samimi, Ph.D., M.P.H.
Marker, Ryan J

University Of Colorado Denver
United States

Effects of a telehealth exercise program for rural cancer survivors with cancer-related fatigue including integrated longitudinal assessments of objective physical function and fatty acid oxidation 5R01CA292482-02 Goli Samimi, Ph.D., M.P.H.
Markowitz, Sanford D.

Case Western Reserve University
United States

A Clinical Trial of Cancer Prevention by Biomarker Based Detections of Barrett's Esophagus and Its Progression 1R01CA295877-01
Markowitz, Sanford D.

Case Western Reserve University
United States

Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablation 5U01CA271867-04 Matthew Young, Ph.D.
Markowitz, Sanford D.

Case Western Reserve University
United States

Validation of Biomarkers for predicting Barrett's esophagus that will or will not: i) progress towards cancer, or ii) recur after ablation 5U01CA271867-04 Matthew Young, Ph.D.
Marshall, David T.

Medical University Of South Carolina
United States

Medical University of South Carolina NCORP Minority/Underserved Community Site 3UG1CA189848-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Marshall, David T.

Medical University Of South Carolina
United States

Medical University of South Carolina NCORP Minority/Underserved Community Site 3UG1CA189848-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Martinez-Conde, Susana

Suny Downstate Medical Center
United States

Novel Perceptual and Oculomotor Heuristics for Enhancing Radiologic Performance 5R01CA258021-05 Guillermo Marquez, Ph.D.
Masters, Gregory A

Christiana Care Health Services, Inc.
United States

Delaware Christiana Care NCORP 3UG1CA189819-11S1 Vanessa A. White, M.P.H.
Masters, Gregory A

Christiana Care Health Services, Inc.
United States

Delaware Christiana Care NCORP 3UG1CA189819-11S1 Vanessa A. White, M.P.H.
Matin, Khalid

Virginia Commonwealth University
United States

VCU Massey Cancer Center Minority/Underserved NCI Community Oncology Research Program 3UG1CA189869-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Matin, Khalid

Virginia Commonwealth University
United States

VCU Massey Cancer Center Minority/Underserved NCI Community Oncology Research Program 3UG1CA189869-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Mcguire, Andrew

Fred Hutchinson Cancer Center
United States

Rational Vaccine Design to prevent HIV-Associated Lymphoma 5R01CA285227-02
Mclouth, Laurie

University Of Kentucky
United States

Pathways, a Hope-Based Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life during Advanced Lung Cancer Treatment 5R01CA283929-03 Brennan Streck, Ph.D., RN, M.P.H.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554