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Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

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About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Greene, Nicholas Perry

University Of Arkansas At Fayetteville
United States

DEVELOPMENT OF TARGETED APPROACHES IN PREVENTION OF CANCER-CACHEXIA 5R01AR075794-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Greene, Nicholas Perry

University Of Arkansas At Fayetteville
United States

DEVELOPMENT OF TARGETED APPROACHES IN PREVENTION OF CANCER-CACHEXIA 5R01AR075794-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Grimm, Lars J

Duke University
United States

Dynamic imaging and tissue biomarker models to delineate indolent from aggressive breast calcifications 4R01CA271237-04 Guillermo Marquez, Ph.D.
Grogan, Eric L

Vanderbilt University Medical Center
United States

Clinical Utility of Biomarkers Driven Management of Indeterminate Pulmonary Nodules 5R01CA252964-05 Claire Zhu, Ph.D.
Groninger, J. Hunter

Medstar Health Research Institute
United States

Cognitive behavioral theory-assisted virtual reality for chronic cancer pain (VR-CAN): device prototype development and feasibility testing 1R21CA299799-01 Brennan Streck, Ph.D., RN, M.P.H.
Groninger, J. Hunter

Medstar Health Research Institute
United States

Cognitive behavioral theory-assisted virtual reality for chronic cancer pain (VR-CAN): device prototype development and feasibility testing 1R21CA299799-01 Brennan Streck, Ph.D., RN, M.P.H.
Gross, Howard M

Dayton Clinical Oncology Program
United States

Dayton Clinical Oncology Program 3UG1CA189957-11S1 Vanessa A. White, M.P.H.
Gross, Howard M

Dayton Clinical Oncology Program
United States

Dayton Clinical Oncology Program 3UG1CA189957-11S1 Vanessa A. White, M.P.H.
Grossman, Douglas

University Of Utah
United States

Electrical impedance dermography as a biomarker for basal and squamous cell carcinoma 1R21CA289101-01A1 Nicholas Hodges, Ph.D.
Gudas, Lorraine J

Weill Medical Coll Of Cornell Univ
United States

CD 1530, an RAR Gamma Agonist for Oral Cavity Squamous Cell Carcinoma Prevention 5R01CA270248-03 Anda Vlad, M.D., Ph.D.
Guo, Xingyi

Vanderbilt University Medical Center
United States

Leveraging Omics and Electronic Health Records Data to study Colorectal Adenoma genetics and Drug Repurposing 1R01CA297582-01A1 Gary Della'Zanna, D.O., M.Sc.
Hall, Daniel Lee

Massachusetts General Hospital
United States

Innovating CBT-I for Cancer Survivors: An Optimization Trial 5R21CA279248-02
Hall, Daniel Lee

Massachusetts General Hospital
United States

Innovating CBT-I for Cancer Survivors: An Optimization Trial 5R21CA279248-02
Halmos, Balazs

Montefiore Medical Center (Bronx, Ny)
United States

Montefiore Academic Communicty NCORP Program 3UG1CA189859-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Halmos, Balazs

Montefiore Medical Center (Bronx, Ny)
United States

Montefiore Academic Communicty NCORP Program 3UG1CA189859-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554