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Consortium for Imaging and Biomarkers (CIB)

The Consortium for Imaging and Biomarkers (CIB) seeks to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and cancer diagnosis by integrating imaging strategies with biomarkers into complementary approaches.

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About the Consortium for Imaging and Biomarkers

The Consortium for Imaging and Biomarkers aims to integrate imaging strategies and biomarker methodologies into a singular complementary approach to cancer detection. Investigators Work in multi-disciplinary teams to perform collaborative studies, exchange information, share knowledge and leverage common resources.

Overdiagnosis (finding cancers that will never affect a person’s health) and false positives (test results that show cancer when none is there) present significant clinical problems in the prevention, detection and treatment of cancer. There is a need to more accurately identify early-stage aggressive cancers and distinguish lesions that are life threatening from those that are not.

The Consortium for imaging and Biomarkers Research Units develop, optimize, and clinically validate novel methods to:

  • Detect aggressive cancers at the earliest stages possible;
  • Reduce overdiagnosis;
  • Reduce false positive tests; and
  • Identify lethal cancers from non-lethal disease.

The goal of the Consortium for imaging and Biomarkers is to develop improved methods for the early detection of aggressive cancer by managing overdiagnosis, reducing false positives and identifying lethal cancers from non-lethal disease using strategies aimed at effective integration and validation of imaging and biomarkers.

Funding Opportunity

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Cremer, Miriam

Cleveland Clinic Lerner Com-Cwru
United States

Single Visit Clinical Validation of ScreenFire, a Low-Cost HPV Test: Efficacy and Cost Effectiveness (SCALE) 5R01CA266059-04 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Curtis, Amarinthia E

Spartanburg Regional Medical Center
United States

Upstate Carolina Consortium - Community Oncology Research Program 3UG1CA239762-06S1 Vanessa A. White, M.P.H.
Curtis, Amarinthia E

Spartanburg Regional Medical Center
United States

Upstate Carolina Consortium - Community Oncology Research Program 3UG1CA239762-06S1 Vanessa A. White, M.P.H.
Curtius, Kathleen M.

University Of California, San Diego
United States

Multiscale modeling of spatiotemporal evolution in Barrett's esophagus 5R01CA270235-03 Asad Umar, D.V.M., Ph.D.
Czerniak, Bogdan A

University Of Tx Md Anderson Can Ctr
United States

Mechanisms of Bladder Cancer Development and Its Therapeutic Vulnerabilities to Preventive and Interventive Therapy. 1P01CA296429-01A1 Howard L. Parnes, M.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Targeting Sphingosine-1-phosphate (S1P1) receptors for the treatment of Aromatase Inhibitors-induced Musculoskeletal Symptoms 5R01CA272147-03 Rachel Altshuler, Ph.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Targeting Sphingosine-1-phosphate (S1P1) receptors for the treatment of Aromatase Inhibitors-induced Musculoskeletal Symptoms 5R01CA272147-03 Rachel Altshuler, Ph.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Inhibition of NLRP3 inflammasome for the treatment of Chemotherapy-induced peripheral neuropathy 1R21CA296516-01 Rachel Altshuler, Ph.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Inhibition of NLRP3 inflammasome for the treatment of Chemotherapy-induced peripheral neuropathy 1R21CA296516-01 Rachel Altshuler, Ph.D.
Daniel-Macdougall, Carrie

University Of Tx Md Anderson Can Ctr
United States

Prebiotic diet intervention to enhance the microbiome and immunotherapy response in melanoma 5R01CA291965-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Dashwood, Roderick H

Texas A&M University Health Science Ctr
United States

Immunoepigenetic targeting of MHC regulators in FAP 5R01CA257559-03
Debes, Jose Daniel

University Of Minnesota
United States

Biomarkers for Early Detection of Hepatitis B-Related Hepatocellular Carcinoma in Hispanics 1R37CA297814-01 Sidney Fu, M.D.
Delaney, Joe R

Medical University Of South Carolina
United States

Biologic rationale of fallopian tube removal to prevent uterine serous carcinoma 1R21CA292343-01A1 Goli Samimi, Ph.D., M.P.H.

Program Contact(s)

Sudhir Srivastava, Ph.D., M.P.H.
Email: sudhir.srivastava@nih.gov

Guillermo Marquez, Ph.D.
Email: guillermo.marquez@nih.gov