Search the DCP's clinical trials database for ongoing clinical trials in prevention, early detection, and the management of symptoms related to cancer and its treatments.
| Title | Intervention | Sponsor Sort descending | Status |
|---|---|---|---|
| An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis | Biopsy Procedure, Biospecimen Collection, EP2/EP4 Antagonist TPST-1495, Esophagogastroduodenoscopy, Gastrointestinal Endoscopy, Questionnaire Administration | National Cancer Institute (NCI) | Not yet recruiting |
| Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus | Biopsy Procedure, Biospecimen Collection, Endoscopic Procedure, Itraconazole, Placebo Administration, Questionnaire Administration, Radiofrequency Ablation | National Cancer Institute (NCI) | Not yet recruiting |
| Testing the SurVaxM Vaccine for Lung Cancer Prevention | Biospecimen Collection, Montanide ISA 51 VG, Questionnaire Administration, SVN53-67/M57-KLH Peptide Vaccine, Sargramostim | National Cancer Institute (NCI) | Not yet recruiting |
| A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer | Medical Device Usage and Evaluation, Tirzepatide | National Cancer Institute (NCI) | Not yet recruiting |
| Obeticholic Acid for Prevention in Barrett's Esophagus | Biospecimen Collection, Esophageal Biopsy, Esophagogastroduodenoscopy, Liver Ultrasonographic Elastography, Obeticholic Acid, Placebo Administration, Questionnaire Administration | National Cancer Institute (NCI) | Recruiting |
| Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial | Biopsy Procedure, Curettage Procedure, Hysterectomy, Megestrol Acetate, Progesterone Only Hormone Replacement Therapy | New Mexico Cancer Research Alliance | Not yet recruiting |
| Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer | Biopsy Procedure, Extended Release Metformin Hydrochloride, Megestrol Acetate, Questionnaire Administration | Northwestern University | Active, not recruiting |
| Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study | Biospecimen Collection, Lisinopril, Liver Ultrasonographic Elastography, Magnetic Resonance Elastography, Magnetic Resonance Imaging, Proton Density Fat Fraction, Questionnaire Administration | Northwestern University | Active, not recruiting |
| Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer | Biopsy, Biospecimen Collection, Bronchoscopy, Extended Release Metformin Hydrochloride, Questionnaire Administration | Northwestern University | Active, not recruiting |
| Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis | Atorvastatin Calcium, Biopsy of Colon, Biospecimen Collection, Placebo Administration, Questionnaire Administration | Northwestern University | Active, not recruiting |
| Mosaic Trial for Stem Cell Transplant Recipients | Enhanced Usual Care (Control) Website, Intervention website | Northwestern University | Recruiting |
| Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps | 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy | NRG Oncology | Recruiting |
| A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer | Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection, Magnetic Resonance Imaging, Quality-of-Life Assessment, Questionnaire Administration, Transvaginal Ultrasound, Ultrasound Imaging | NRG Oncology | Recruiting |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability | Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Survey Administration, Whole-Brain Radiotherapy | NRG Oncology | Recruiting |
| Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer | Biospecimen Collection, Diagnostic Imaging Testing, Excisional Biopsy, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping | NRG Oncology | Recruiting |
| Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors | Arm 1: Computerized Cognitive Training-Global Stimulation Games, Arm 2: Computerized Cognitive Training-Neuroplasticity Games | NRG Oncology | Recruiting |
| Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment | Counseling, Health Education, Interview, Medical Chart Review, Monitoring, Questionnaire Administration | NRG Oncology | Recruiting |
| Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer | Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy, Intensity-Modulated Radiation Therapy, Magnetic Resonance Imaging, MnSOD Mimetic BMX-001, Placebo Administration, Questionnaire Administration | NRG Oncology | Recruiting |
| E-Mindfulness Approaches for Living After Breast Cancer | Meditation Only Control Group, Mindfulness (MAPs) Digital App, Mindfulness (MAPs) Live Online | NRG Oncology | Recruiting |
| Comparing Radiation Therapy to Usual Care for Patients With High-Risk Bone Asymptomatic Metastases, PREEMPT Trial | Best Practice, Biospecimen Collection, Bone Metastases Treatment, Computed Tomography, Conventional Radiotherapy, Magnetic Resonance Imaging, Patient Observation, Questionnaire Administration, Stereotactic Body Radiation Therapy | NRG Oncology | Recruiting |