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Principal Investigator
Augusto C. Ochoa
Awardee Organization

Lsu Health Sciences Center
United States

Fiscal Year
2025
Activity Code
UG1
Early Stage Investigator Grants (ESI)
Not Applicable
Project End Date

Gulf South Clinical Trials Network (Gulf South NCORP)

The Gulf South Clinical Trials Network - NCORP (Gulf South -NCORP) and the Ochsner-Community-NCORP, the two NCORPs in Louisiana, have both met the objectives proposed for the last funding cycle, expanding access to and significantly increasing the number of patients participating in clinical trials in Louisiana and the Gulf South region. These successful NCORPs have agreed to come together to form the Gulf South NCORP, which will have as its primary affiliates the LSU – Cancer Center New Orleans (LSU-CC-New Orleans), LSU – Feist Weiller Cancer Center Shreveport (LSU-FWCC-Shreveport), Mary Bird Perkins Cancer Center (MBPCC) and the Ochsner-Cancer Center (Ochsner). The new Gulf South NCORP will provide cancer care and access to clinical trials for >50% of new cancer cases in the region, expand the number of sites offering access to clinical trials from 22 to 42 sites. The Gulf South NCORP will bring additional resources including the Louisiana Tumor SEER registry (LTR-SEER) and the state-wide cancer screening programs such as the Louisiana Breast and Cervical Health Program (LBCHP), and the Louisiana Comprehensive Cancer Control Program (LCCCP). In addition we will benefit from ongoing research led by our investigators. The new Gulf South NCORP has also expanded its network with major health providers in the region including the Veterans Administration Hospital (New Orleans), Woman’s Hospital (the largest dedicated clinical center for women’s health) in Baton Rouge and the Christus Health community sites. The new Gulf South NCORP has garnered the support of the Louisiana Department of Health Secretary and the Governor, who are developing a cancer care plan for the state (Taking Aim at Cancer in Louisiana Collaborative -TACL), where the Gulf South M/U CTN is the major provider of state-wide cancer clinical trials. This support will help us to continue increasing the participation of patients in NCORP and non-NCORP studies. To achieve our goals we will implement the following three strategies. 1. Expand the number of sites through additional partnerships with community organizations such as FQHC’s where we will test novel approaches to increase the participation of community physicians providing care to cancer patients in the region; 2. Support the development of research initiated by our investigators to understand the impact created by cancer in our region and 3. Increase our participation in national trials supported by NCORP and other organizations to expand the scope and depth of trials offered to our patients.

Publications

  • Kircher S, Duan F, An N, Gareen IF, Sicks JD, Sadigh G, Suga JM, Kehn H, Mehan PT, Bajaj R, Hanson DS, Dalia SM, Acoba JD, Yasar DG, Park ER, Wagner LI, Carlos RC. Patient-Reported Financial Burden of Treatment for Colon or Rectal Cancer. JAMA network open. 2024 Jan 2;7(1):e2350844. PMID: 38194233
  • Sadigh G, Duan F, An N, Gareen ID, Sicks J, Suga JM, Kehn H, Mehan PT, Bajaj R, Hanson DS, Dalia SM, Acoba JD, Yasar DG, Taylor MA, Park E, Wagner LI, Kircher SM, Carlos RC. Financial Hardship Among Patients With Early-Stage Colorectal Cancer. JAMA network open. 2024 Sep 3;7(9):e2431967. PMID: 39287948
  • Dunsmore VJ, Snyder BS, Gareen IF, Lehman CD, Khan SA, Romanoff J, Gatsonis C, Corsetti RL, Rahbar H, Spell DW, Han LK, Bumberry JR, Miller KD, Sparano JA, Comstock C, Park E, Wagner LI, Carlos RC. Quality of Life Among Patients With Ductal Carcinoma In Situ. JAMA network open. 2025 Jul 1;8(7):e2518887. PMID: 40608342
  • Chou SS, Romanoff J, Lehman CD, Khan SA, Carlos R, Badve SS, Xiao J, Corsetti RL, Javid SH, Spell DW, Han LK, Sabol JL, Bumberry JR, Gareen IF, Snyder BS, Gatsonis C, Wagner LI, Wolff AC, Miller KD, Sparano JA, Comstock CE, Rahbar H. Preoperative Breast MRI for Newly Diagnosed Ductal Carcinoma in Situ: Imaging Features and Performance in a Multicenter Setting (ECOG-ACRIN E4112 Trial). Radiology. 2021 Oct;301(1):66-77. Epub 2021 Aug 3. PMID: 34342501