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Principal Investigator
Jared Acoba
Awardee Organization

University Of Hawaii At Manoa
United States

Fiscal Year
2025
Activity Code
UG1
Early Stage Investigator Grants (ESI)
Not Applicable
Project End Date

The Hawaii Minority/Underserved NCORP

The overall goal of the Hawaiʻi National Cancer Institute Community Oncology Research Program (NCORP) is to provide access and facilitate enrollment of Hawaii’s unique population to NCI sponsored trials. Thus we will work to accrue a representative population of our catchment area. Our NCORP is the primary provider of NCI clinical trials and cancer care delivery research (CCDR) in the State of Hawaiʻi. The Hawaiʻi NCORP supports an integrated network of affiliates and sub-affiliates with an extensive menu of cancer studies, research infrastructure and data management. Our NCORP has successfully extended CCDR studies from the originally designated sites to other hospital affiliate sites with plans to further extend them to physician office sites. We solicit community input from patient advocates in our community to review the suitability of trials as well as to address their healthcare needs. Non-medical oncology community investigators and staff have leadership responsibility in imaging, prevention and CCDR studies. Our NCORP leaders have extensive experience in cancer clinical trials, health care delivery and issues affecting our unique population. They have served on multiple NCI committees. Participation in NCI’s personalized medicine, cancer control, prevention, treatment and CCDR research will further reduce cancer health care gaps and the cancer burden for the people of Hawaiʻi and beyond.

Publications

  • Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE Jr, Dees EC, Goetz MP, Olson JA Jr, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin PM, Keane MM, Gomez Moreno HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW Jr. Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer. The New England journal of medicine. 2018 Jul 12;379(2):111-121. Epub 2018 Jun 3. PMID: 29860917
  • Braun-Inglis CM, Dressler EV, Myers JS, Benson AB 3rd, Flannery M, Good M, Denicoff A, Berenberg JL, DeTroye AT, O'Brien B, Kottschade L, Omatsu DA, Kittel CA, Nightingale CL, Foust M, Lesser GJ. Defining the Role of the Advanced Practice Provider Within the National Cancer Institute Community Oncology Research Program. JCO oncology practice. 2024 Feb;20(2):239-246. Epub 2024 Jan 4. PMID: 38175992
  • Kircher S, Duan F, An N, Gareen IF, Sicks JD, Sadigh G, Suga JM, Kehn H, Mehan PT, Bajaj R, Hanson DS, Dalia SM, Acoba JD, Yasar DG, Park ER, Wagner LI, Carlos RC. Patient-Reported Financial Burden of Treatment for Colon or Rectal Cancer. JAMA network open. 2024 Jan 2;7(1):e2350844. PMID: 38194233
  • Albain KS, Gray RJ, Makower DF, Faghih A, Hayes DF, Geyer CE, Dees EC, Goetz MP, Olson JA, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Wood WC, Keane MM, Gomez HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW, Sparano JA. Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial. Journal of the National Cancer Institute. 2021 Apr 6;113(4):390-399. PMID: 32986828
  • Sadigh G, Duan F, An N, Gareen ID, Sicks J, Suga JM, Kehn H, Mehan PT, Bajaj R, Hanson DS, Dalia SM, Acoba JD, Yasar DG, Taylor MA, Park E, Wagner LI, Kircher SM, Carlos RC. Financial Hardship Among Patients With Early-Stage Colorectal Cancer. JAMA network open. 2024 Sep 3;7(9):e2431967. PMID: 39287948