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Principal Investigator
Kathleen H Mooney
Awardee Organization

University Of Utah
United States

Fiscal Year
2020
Activity Code
R01
Project End Date

Remote COVID-19 Symptom Tracking and Improved Cancer Symptom Control for Cancer Patients at Home During the Pandemic

In response to the COVID-19 pandemic, there is an opportunity to rapidly flex platforms for remote cancer symptom tracking and management to incorporate COVID-19 symptom monitoring and reinforce risk-reducing precautions. It is critical for cancer patients at home to monitor early indications of COVID-19 symptoms, to adhere to mitigation strategies, as well as to manage their cancer-related symptoms so that they can decrease the need to utilize the emergency department or unplanned hospitalizations for symptom care, which is a common occurrence during cancer care. Remote monitoring adds a layer of home-based support which can benefit all cancer patients and is not restricted to geographic proximity to oncology providers or distance from a cancer center. Our Symptom Care at Home (SCH) system, utilized for our currently funded R01CA206522 project to monitor and manage patient-reported (PRO) cancer symptoms, includes these necessary elements: remote PRO symptom monitoring, patient self-management information, and oncology provider (nurse practitioner) notification of symptoms exceeding pre-set thresholds. We propose adding two aims to R01CA206522 in response to PA-18-935 Urgent Competitive Revision to an Existing NIH Grant. The overall purpose of this supplement is to describe the impacts of COVID-19 on cancer patients’ well-being at home and evaluate, through a randomized clinical trial, if a systematic patient-reported outcomes (PRO) reporting process improves cancer care during a pandemic as compared to usual care. Specific Aims include: 1) describe patient-reported COVID-19 and cancer symptom trajectories over time, COVID-19 social distancing and hygiene practices, and COVID-19 related cancer treatment and daily living impacts on cancer patients receiving the SCH-COVID intervention and 2) compare the SCH-COVID intervention to enhanced usual care on health care utilization, COVID-19 diagnosis and outcomes, cancer treatment delays or changes, and patient-reported global health, anxiety, mood, and feelings of social isolation.

Publications

  • Nicholson B, Moraitis AM, Cawley K, Wong B, Echeverria C, Mooney K. Step count and symptom severity during cancer treatment using the Symptom Care at Home digital platform. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2025 Aug 4;33(8):747. PMID: 40758176
  • Gullatte M, Nicholson B, Sloss E, Alekhina N, Marie Moraitis A, Iacob E, Donaldson G, Mooney K. Digital Patient-Reported Cancer Symptom Management: Comparison of Black and White Participants. Cancer medicine. 2025 Jul;14(13):e71026. PMID: 40631393
  • Mooney K, Gullatte M, Iacob E, Alekhina N, Nicholson B, Sloss EA, Lloyd J, Moraitis AM, Donaldson G. Essential Components of an Electronic Patient-Reported Symptom Monitoring and Management System: A Randomized Clinical Trial. JAMA network open. 2024 Sep 3;7(9):e2433153. PMID: 39269704

Clinical Trials

Study Name Clinical Trial ID
SymptomCare@Home: Deconstructing an Effective Symptom Management Intervention NCT02779725