NCI’s HIV/Cervical Cancer Prevention ‘CASCADE’ Clinical Trials Network is a cooperative agreement-funded program focused on pragmatic clinical trials to optimize the cervical cancer screening, management, and precancer treatment cascade for women living with HIV.
On This Page
- All Headings will automatically be pulled in to this list.
- Do not edit the content on this template.
About CASCADE
CASCADE is a global partnership focused on optimizing the cervical cancer screening, management, and pre-cancer treatment cascade for women living with HIV.
Funding Opportunities
Related Funding Opportunities and Training Resources for CASCADE Grantees.
Organizational Units
The ‘CASCADE’ Network consists of the following organizational units:
- 1 Network Coordinating Center
-
Organizational Unit
Principal Investigator(s)
Institution(s)
Grant No.
CASCADE Network Coordinating Center (CNCC)
Suzanne Siminski, M.S., M.B.A., and KyungMann Kim, Ph.D.
Frontier Science, with
University of Wisconsinsupported via RFA-CA-21-045
- 3 Research Bases
-
Organizational Unit
Principal Investigator(s)
Institution(s)
Grant No.
Research Base 1 (RB1)
Rachel Winer, Ph.D., M.P.H. and
Elizabeth Brown, Sc.D., M.S.University of Washington, with
Fred Hutchinson Cancer Research CenterResearch Base 2 (RB2)
Timothy Wilkin, M.D., M.P.H., Anna Giuliano, Ph.D., and
Carla Chibwesha, M.D., M.Sc.University of California San Diego with Moffitt Cancer Center and University of North Carolina at Chapel Hill
Research Base 3 (RB3)
Jennifer Smith, Ph.D., M.P.H., Michael Hudgens, Ph.D., and Lameck Chinula, M.D., M.P.H.
University of North Carolina at Chapel Hill
supported via RFA-CA-21-046
- 9 Clinical Sites
-
Organizational Unit
Principal Investigator(s)
Institution(s)
Grant No.
Clinical Trials Site 1 (CS1): Uganda
Betty Mwesigwa, M.B.Ch.B., M.Sc.
Makerere University Walter Reed Project, with US Military HIV Research Program and Uganda Cancer Institute
Clinical Trials Site 2 (CS2): Kenya
Michael Chung, M.D., Ph.D., M.P.H. and Samah Sakr, M.B.Ch.B.
Emory University, with Coptic Hope Center for Infectious Diseases and Kenyatta National Hospital
Clinical Trials Site 3 (CS3): Botswana
Scott Dryden-Peterson, M.D., M.S. and Doreen Ramogola-Masire, M.B.B.S., Ph.D., M.P.H.
Brigham and Women's Hospital, with Botswana Harvard AIDS Institute Partnership
Clinical Trials Site 4 (CS4): US/Georgia
Lisa Flowers, M.D., M.P.H. and
Anandi Sheth, M.D., M.Sc.
Emory University
Clinical Trials Site 5 (CS5): Rwanda
Gad Murenzi, M.D., M.S., Kathryn Anastos, M.D., and Rubagumya Fidel, M.D., M.P.H.
Research for Development, Albert Einstein College of Medicine, with Rwanda Military Hospital
Clinical Trials Site 6 (CS6): Kenya
Nelly Mugo, M.B.Ch.B., M.P.H., and Kenneth Ngure, Ph.D., M.P.H., M.Sc.
Kenya Medical Research Institute (KEMRI), with Jomo Kenyatta University of Agriculture and Technology
Clinical Trials Site 7 (CS7): Zimbabwe
Chirenje Zvavahera, M.D., and Bothwell Guzha, M.B.Ch.B, M.Phil
University of California, San Francisco, with University of Zimbabwe
Clinical Trials Site 8 (CS8): US/Maryland
Clement Adebamowo, B.M.Ch.B., Sc.D., and Gregory Taylor, M.D.
University of Maryland, Baltimore
Clinical Trials Site 9 (CS9): South Africa
Nivashnee Naicker, M.D., M.P.H, M.A.S.
Centre for the AIDS Programme of Research in South Africa (CAPRISA)
three sites supported via RFA-CA-21-047; six additional sites supported via RFA-CA-22-051
Unified Network Initiative to Enhance Community Dialogue and Site Education (UNITED)
UNITED provides a dynamic framework for both ULACNet and CASCADE to promote activities that build shared trust between researchers and communities, and to ensure that research outcomes and benefits are disseminated to study participants and the broader community.
UNITED will enhance both the ULACNet and CASCADE networks by:
- Providing a forum for network members to share knowledge and lessons learned on effective strategies for enhancing study recruitment and community engagement;
- Providing training and educational opportunities for CASCADE and ULACNet members; and
- Providing clinical trial resources for network study participants, their families, and the public.
Learn more about UNITED and view recordings of community engagement sessions
Program Contact(s)
Email: cascade@nih.gov
Phone: 240-276-7332
Fax: 240-276-7828
Program Director
Vikrant Sahasrabuddhe, M.B.B.S., Dr.P.H.
Email: vikrant.sahasrabuddhe@nih.gov