Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Screening Strategies Among High-risk Populations for Anal Cancer

Status

Recruiting

NCT ID

NCT06628570

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

Intervention

Anal Cytology, CINtec®PLUS, Genotyping of anal hrHPV infection, HRA + Biopsy

Condition

Neoplasms, HPV-Related Anal Squamous Cell Carcinoma

Investigators

Canhua Xiao, PhD, RN, Lisa Flowers, MD, MPH, Isabella Rosa-Cunha, MD, Isabella Rosa-Cunah, MD, Lisa Flowers, MD

See list of participating sites