Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors

This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.

Intervention

Biospecimen Collection, Laboratory Biomarker Analysis, Questionnaire Administration

Condition

Cancer Survivor, Osteosarcoma

Investigators

Ramamoorthy Nagasubramanian, Jill P. Ginsberg, Alan K. Ikeda, Nichole L. Bryant, Robert M. Cooper, Smita Bhatia, Mark A. Ranalli, Anderson (Andy) B. Collier, Karen E. Effinger, Jason M. Fixler, Kamnesh R. Pradhan, Nkechi I. Mba, Luis A. Clavell, Rajen Mody, Robert J. Hayashi, Rajaram Nagarajan, Donald T. Beam, William B. Slayton, Timothy P. Garrington, Ayman A. El-Sheikh, Mariko Sato, Ray C. Pais, Patrick J. Leavey, Mary L. Schmidt, Douglas S. Hawkins, Nina S. Kadan-Lottick, Rene Y. McNall-Knapp, Marcio H. Malogolowkin, Jessica Boklan, Sheri L. Spunt, Denise A. Rokitka, Judy L. Felgenhauer, Vlad C. Radulescu, Michael W. Bishop, Danielle N. Friedman, Lars M. Wagner, William D. Roberts, Fouad M. Hajjar, Kathleen J. Yost, Jennifer J. Greene Welch, A. L. Frazier, Sarah J. McKillop, Rabi Hanna, Jessica A. Bell, Emad K. Salman, Saro H. Armenian, David O. Walterhouse, Robert J. Vasquez, Keith J. August, Nadine P. SantaCruz, Anne-Marie R. Langevin, Carla B. Golden, Vinod K. Gidvani-Diaz, Tara O. Henderson, Wendy Allen-Rhoades, Jean M. Tersak, Roland L. Chu, Stuart H. Gold, Laura A. Campbell, Gregory E. Halligan, Steven J. Kuerbitz, Samantha L. Mallory, Wade T. Kyono, Dana A. Obzut, Jaime M. Libes

See list of participating sites