S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER)

This randomized clinical trial studies prophylactic colony stimulating factor management in
patients with breast, colorectal or non-small cell lung cancer receiving chemotherapy and
with risk of developing febrile neutropenia. Patients receiving chemotherapy may develop
febrile neutropenia. Febrile neutropenia is a condition that involves fever and a low number
of neutrophils (a type of white blood cell) in the blood. Febrile neutropenia increases the
risk of infection. Colony stimulating factors are medications sometimes given to patients
receiving chemotherapy to prevent febrile neutropenia. Colony stimulating factors are given
to patients based on guidelines. Some clinics have an automated system that helps doctors
decide when to prescribe them when there is a high risk of developing febrile neutropenia.
Gathering information about the use of an automated system to prescribe prophylactic colony
stimulating factor may help doctors use colony stimulating factor when it is needed.

Intervention

Preventive Intervention, Quality-of-Life Assessment, Questionnaire Administration

Condition

Febrile Neutropenia, Stage 0 Breast Cancer, Stage 0 Colorectal Cancer, Stage 0 Non-Small Cell Lung Cancer, Stage I Colorectal Cancer, Stage IA Breast Cancer, Stage IA Non-Small Cell Lung Carcinoma, Stage IB Breast Cancer, Stage IB Non-Small Cell Lung Carcinoma, Stage IIA Breast Cancer, Stage IIA Colorectal Cancer, Stage IIA Non-Small Cell Lung Carcinoma, Stage IIB Breast Cancer, Stage IIB Colorectal Cancer, Stage IIB Non-Small Cell Lung Carcinoma, Stage IIC Colorectal Cancer, Stage IIIA Breast Cancer, Stage IIIA Colorectal Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Breast Cancer, Stage IIIB Colorectal Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IIIC Breast Cancer, Stage IIIC Colorectal Cancer, Stage IV Breast Cancer, Stage IV Non-Small Cell Lung Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer

Investigators

Scott Ramsey

See list of participating sites