Major Program
Supportive Care and Symptom Management
Sponsor
Mayo Clinic
Status
Active, not recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT02598726
This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract [standardized]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer. Curcumin is a spice similar to turmeric and works by decreasing the chemical moderators that produce inflammation in the body. Piperine is pepper and works by increasing the amount of curcumin available in the body when taken with curcumin. Giving curcumin together with piperine may reduce inflammation and discomfort from a ureteric stent in older patients with cancer.
Intervention
Curcumin, Laboratory Biomarker Analysis, Piperine Extract (Standardized), Quality-of-Life Assessment
Condition
Bladder Spasm, Malignant Neoplasm, Pain, Urinary Urgency
Investigators
Aminah Jatoi, M.D.