Research Group
Nutritional Science
Sponsor
Brigham and Women's Hospital
Status
Active, not recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT02239874
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial
in 25,875 U.S. men and women investigating whether taking daily dietary supplements of
vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of
developing cancer, heart disease, and stroke in people who do not have a prior history of
these illnesses. This ancillary study is being conducted among participants in VITAL and will
examine whether vitamin D effects mammographic breast density, mammographic texture features,
and gene expression profiles in breast biopsy tissue.
in 25,875 U.S. men and women investigating whether taking daily dietary supplements of
vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of
developing cancer, heart disease, and stroke in people who do not have a prior history of
these illnesses. This ancillary study is being conducted among participants in VITAL and will
examine whether vitamin D effects mammographic breast density, mammographic texture features,
and gene expression profiles in breast biopsy tissue.
Intervention
Vitamin D and fish oil placebo, Vitamin D and fish oil, Fish oil and vitamin D placebo, Vitamin D placebo and fish oil placebo
Condition
Benign Breast Disease
Investigators
Rulla M Tamimi, ScD, Kathy Rexrode, MD