This phase II trial is studying how well giving acetylsalicylic acid together with
eflornithine works in treating patients at high risk for colorectal cancer. Chemoprevention
is the use of certain drugs to keep cancer from forming. The use of acetylsalicylic acid and
eflornithine may prevent colorectal cancer.
Aspirin, Eflornithine, Laboratory Biomarker Analysis, Placebo, Telephone-Based Intervention