CA-IX, p16, Proliferative Markers, and HPV in Diagnosing Cervical Lesions in Patients With Abnormal Cervical Cells

This research trial studies carbonic anhydrase 9 (CA-IX), p16, proliferative markers, and
human papilloma virus (HPV) in diagnosing cervical lesions in patients with abnormal cervical
cells. Studying biomarkers in abnormal cervical cells may improve the ability to find
cervical lesions and plan effective treatment.

Intervention

Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis

Condition

Atypical Endocervical Glandular Cell of Undetermined Significance, Atypical Endometrial Hyperplasia, Human Papillomavirus Infection, Stage 0 Cervical Cancer AJCC v7

Investigators

Shu-Yuan liao, Shoji Nagao, Daisuke Aoki, Jason D. Wright, Benjamin T. Marchello, Jay W. Carlson, Keun H. Lee, Timothy D. Moore, Tashanna K. Myers, Laurie A. Small, Takayuki Enomoto, Toshiaki Nakamura, Yoshiki Kudo, Richard G. Moore, Sang-Wun Kim, Yoichi Aoki, Nicola M. Spirtos, Hidemichi Watari, Keiichi Fujiwara, John W. Byron, Chi-Heum Cho, Gretchen E. Glaser, Kwang-Beom Lee, Takashi Sawasaki, Kazuhiro Takehara, Katherine M. Moxley, Scott E. Lentz, Joo-Hyun Nam, Kidong Kim, Jae W. Kim, Jae-Hoon Kim, Evelyn L. Fleming, Jong-Min Lee, Enrique Hernandez, Hideki Tokunaga, Joyce Varughese

See list of participating sites