Major Program
Phase 0 I II Cancer Prevention Clinical Trials Program
Research Group
Gastrointestinal and Other Cancers
Sponsor
Mayo Clinic
Status
Completed
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT01950403
This randomized phase I trial studies the side effects and best dose of linaclotide acetate in preventing colorectal cancer in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of linaclotide acetate may prevent colorectal cancer.
Intervention
linaclotide acetate, placebo, pharmacological study, laboratory biomarker analysis
Condition
Colorectal Cancer, Healthy, no Evidence of Disease
Investigators
Paul Limburg