Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia

Major Program(s) or Research Group(s)

  • Gastrointestinal and Other Cancers
  • Phase 0/I/II Cancer Prevention Clinical Trials Program

Sponsor

National Cancer Institute (NCI)

Status

Recruiting

ClinicalTrials.gov ID

For more information, see ClinicalTrials.gov NCT02782949

This randomized phase IIb trial studies how well curcumin works in preventing gastric cancer
in patients with chronic atrophic gastritis and/or gastric intestinal metaplasia. Curcumin is
an antioxidant compound found in plants that may stop the growth of tumor cells by blocking
some of the enzymes needed for cell growth.

Intervention

Curcumin, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Placebo Administration

Condition

Chronic Atrophic Gastritis

Investigators

Ricardo L. Dominguez, Marcia R. Cruz-Correa

See list of participating sites