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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Mehrara, Babak J

Sloan-Kettering Inst Can Research
United States

Mechanisms of racial disparity in breast cancer-related lymphedema 5R01CA278599-04 Asad Umar, D.V.M., Ph.D.
Deng, Gary E

University Of California-Irvine
United States

Acupuncture to Improve Outcomes in Patients with Sepsis: a Randomized Controlled Trial 7R21CA286330-03 Goli Samimi, Ph.D., M.P.H.
Pozdeyev, Nikita

University Of Colorado Denver
United States

Genetic architecture of thyroid cancer and its clinical utility 5R21CA282380-02 Wendy Wang, Ph.D., M.Sc.
Webster, Nicholas J

Veterans Medical Research Fdn/San Diego
United States

The Effect of Time-Restricted Eating on the Efficiency of Chemo- and Hormonal-Therapy in Breast Cancer 5R21CA288777-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Lee, Richard T

Beckman Research Institute/City Of Hope
United States

A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy 1R21CA260447-01A1 Rachel Altshuler, Ph.D.
Xu, Xiangxi Mike

University Of Miami School Of Medicine
United States

Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy 5R01CA286527-02 Rachel Altshuler, Ph.D.
Hui, David

University Of Tx Md Anderson Can Ctr
United States

Strategies for Personalizing Oxygen and support Therapies for dyspnea in Oncology 5R01CA288515-02 Brennan Streck, Ph.D., RN, M.P.H.
Bower, Julienne E

University Of California Los Angeles
United States

Mindfulness Meditation for Younger Breast Cancer Survivors: Testing Digital Interventions in Clinical and Community Settings 5R01CA282416-02 Brennan Streck, Ph.D., RN, M.P.H.
Mosher, Catherine E

Indiana University Indianapolis
United States

Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal Cancer 5R01CA289486-02 Asad Umar, D.V.M., Ph.D.
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Rogers, Laura Q

University Of Alabama At Birmingham
United States

Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors 5R01CA235598-06 Gabriela Riscuta, M.D., CNS
Hanks, Brent Allen

Univ Of North Carolina Chapel Hill
United States

Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities 5R01CA251136-06 Marjorie Perloff, M.D.
Sedrak, Mina S

University Of California Los Angeles
United States

Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline 5R01CA280088-03 Goli Samimi, Ph.D., M.P.H.
Peppone, Luke Joseph

University Of Rochester
United States

High-dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients 5R01CA258349-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Wang, Hsiao-Lan

University Of Alabama At Birmingham
United States

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain after Head and Neck Cancer Treatment 5R01CA244947-06 Goli Samimi, Ph.D., M.P.H.

Clinical Trials

Status
Title Sort ascending Intervention Sponsor Status
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment Children's Oncology Group Active, not recruiting
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia Laboratory Biomarker Analysis, Simplified Patient Care Strategy ECOG-ACRIN Cancer Research Group Active, not recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention Alliance for Clinical Trials in Oncology Recruiting
Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer Endocrine therapy interruption ETOP IBCSG Partners Foundation Active, not recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting