The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.
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About Supportive Care and Symptom Management
The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).
Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.
Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.
Selected Topics
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Research
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Resources
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Building Bridges in Cancer Symptom Science Webinar SeriesThis series is aimed at bringing together interdisciplinary researchers in cancer symptom science to share their expertise and further discussions in the field.
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DCP Early Career Scientist Spotlight Research Seminar SeriesThis seminar series highlights nominated early career scientists who are advancing research within the areas supported by DCP.
Funding Opportunities
No matching Funding Opportunities were found.
Grantee Details
Clinical Trials
| Title | Intervention | Sponsor | Status Sort descending |
|---|---|---|---|
| Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer | Fulvestrant, Letrozole, Palbociclib, Quality-of-Life Assessment, Questionnaire Administration | Alliance for Clinical Trials in Oncology | Active, not recruiting |
| Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer | Carboplatin, Comprehensive Geriatric Assessment, Pembrolizumab, Pemetrexed, Quality-of-Life Assessment, Questionnaire Administration | Alliance for Clinical Trials in Oncology | Active, not recruiting |
| Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer | Chemotherapy, Functional Assessment, Questionnaire Administration | SWOG Cancer Research Network | Active, not recruiting |
| Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy | Best Practice, Exercise Counseling, Exercise Intervention, Magnetic Resonance Imaging, Neuropathy Assessment, Questionnaire Administration | University of Rochester NCORP Research Base | Active, not recruiting |
| Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma | Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment | Children's Oncology Group | Active, not recruiting |
| Relaxation for Women With Breast Cancer Undergoing Radiotherapy | Questionnaires, Relaxation Program, Saliva Testing | M.D. Anderson Cancer Center | Active, not recruiting |
| Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission | Behavioral Intervention, Compliance Monitoring, Laboratory Biomarker Analysis, Mercaptopurine, Questionnaire Administration, Standard Follow-Up Care | Children's Oncology Group | Active, not recruiting |
| Treating Breast Cancer Patients Undergoing Trastuzumab Treatment With Carvedilol to Reduce Incidence of Heart Failure | Carvedilol | Mayo Clinic | Active, not recruiting |
| Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant | Allogeneic Hematopoietic Stem Cell Transplantation, Lactobacillus plantarum strain 299, Lactobacillus plantarum strain 299v, Placebo Administration | Children's Oncology Group | Active, not recruiting |
| Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors | Entecavir, Tenofovir Disoproxil Fumarate, Best Practice, Tenofovir Alafenamide | SWOG Cancer Research Network | Active, not recruiting |
News and Events
Personalised Risk in Lung Screening
Date Posted: April 24, 2025
Cancer Cachexia: From Preclinical Models to Bedside Interventions
Date Posted: March 25, 2025
Survivorship in Patients with Multiple Myeloma Treated with Chimeric Antigen Receptor T-Cell Therapy
Date Posted: March 25, 2025