The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.
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About Supportive Care and Symptom Management
The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).
Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.
Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.
Selected Topics
- HEAL Initiative
- Patient Resources on Side Effects of Cancer Treatment
- Patient Resources on Coping with Cancer
Resources
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Building Bridges in Cancer Symptom Science Webinar SeriesThis series is aimed at bringing together interdisciplinary researchers in cancer symptom science to share their expertise and further discussions in the field.
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DCP Early Career Scientist Spotlight Research Seminar SeriesThis seminar series highlights nominated early career scientists who are advancing research within the areas supported by DCP.
Funding Opportunities
No matching Funding Opportunities were found.
Grantee Details
Clinical Trials
| Title | Intervention | Sponsor | Status |
|---|---|---|---|
| Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors | Arm 1: Computerized Cognitive Training-Global Stimulation Games, Arm 2: Computerized Cognitive Training-Neuroplasticity Games | NRG Oncology | Active, not recruiting |
| Vitamin D for Prostate Endocrine Therapy | Biospecimen Collection, D Vitamin, Dual X-ray Absorptiometry, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration | University of Rochester | Recruiting |
| Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel | Monosialotetrahexosylganglioside, Paclitaxel, Placebo Administration, Quality-of-life assessment, Questionnaire Administration | Alliance for Clinical Trials in Oncology | Active, not recruiting |
| A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients | Biospecimen Collection, Letermovir | Children's Oncology Group | Recruiting |
| A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma | Archive Sample Retrieval, Biospecimen Collection, Electronic Health Record Review, Magnetic Resonance Imaging, Survey Administration | Children's Oncology Group | Recruiting |
| Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy | fractionated stereotactic radiosurgery (FSRS), single fraction stereotactic radiosurgery (SSRS) | Wake Forest University Health Sciences | Active, not recruiting |
| A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia | Biospecimen Collection, Clinical Evaluation, Neurocognitive Assessment, Questionnaire Administration, Survey Administration | Children's Oncology Group | Recruiting |
| Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer | Biospecimen Collection, Diagnostic Imaging Testing, Excisional Biopsy, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping | NRG Oncology | Recruiting |
| Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy | Biospecimen Collection, Cryocompression Therapy, Pneumatic Compression Therapy, Quality-of-Life Assessment, Questionnaire Administration | SWOG Cancer Research Network | Recruiting |
| Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma | Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment | Children's Oncology Group | Active, not recruiting |
News and Events
Harnessing Studies of Diet and the Gut Microbiome to Reduce Colorectal Cancer Burden
Date Posted: April 29, 2025
Personalised Risk in Lung Screening
Date Posted: April 24, 2025
Cancer Cachexia: From Preclinical Models to Bedside Interventions
Date Posted: March 25, 2025