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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Deng, Gary E

University Of California-Irvine
United States

Acupuncture to Improve Outcomes in Patients with Sepsis: a Randomized Controlled Trial 7R21CA286330-03 Goli Samimi, Ph.D., M.P.H.
Pozdeyev, Nikita

University Of Colorado Denver
United States

Genetic architecture of thyroid cancer and its clinical utility 5R21CA282380-02 Wendy Wang, Ph.D., M.Sc.
Webster, Nicholas J

Veterans Medical Research Fdn/San Diego
United States

The Effect of Time-Restricted Eating on the Efficiency of Chemo- and Hormonal-Therapy in Breast Cancer 5R21CA288777-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Xu, Xiangxi Mike

University Of Miami School Of Medicine
United States

Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy 5R01CA286527-02 Rachel Altshuler, Ph.D.
Hui, David

University Of Tx Md Anderson Can Ctr
United States

Strategies for Personalizing Oxygen and support Therapies for dyspnea in Oncology 5R01CA288515-02 Brennan Streck, Ph.D., RN, M.P.H.
Bower, Julienne E

University Of California Los Angeles
United States

Mindfulness Meditation for Younger Breast Cancer Survivors: Testing Digital Interventions in Clinical and Community Settings 5R01CA282416-02 Brennan Streck, Ph.D., RN, M.P.H.
Mosher, Catherine E

Indiana University Indianapolis
United States

Acceptance and Commitment Therapy for Patient Fatigue Interference and Caregiver Burden in Advanced Gastrointestinal Cancer 5R01CA289486-02 Asad Umar, D.V.M., Ph.D.
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Rogers, Laura Q

University Of Alabama At Birmingham
United States

Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors 5R01CA235598-06 Gabriela Riscuta, M.D., CNS
Hanks, Brent Allen

Univ Of North Carolina Chapel Hill
United States

Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities 5R01CA251136-06 Marjorie Perloff, M.D.
Sedrak, Mina S

University Of California Los Angeles
United States

Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline 5R01CA280088-03 Goli Samimi, Ph.D., M.P.H.
Peppone, Luke Joseph

University Of Rochester
United States

High-dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients 5R01CA258349-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Wang, Hsiao-Lan

University Of Alabama At Birmingham
United States

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain after Head and Neck Cancer Treatment 5R01CA244947-06 Goli Samimi, Ph.D., M.P.H.
Hu, Shuiying

Ohio State University
United States

Targeting neuronal transport to ameliorate vincristine neurotoxicity 5R01CA272254-03 Rachel Altshuler, Ph.D.
Palesh, Oxana G

Virginia Commonwealth University
United States

Multicenter Randomized Controlled Trial of Brief Behavioral Therapy for Cancer Related Insomnia 5R01CA239714-07 Brandy Heckman-Stoddard, Ph.D., M.P.H.

Clinical Trials

Status
Title Intervention Sponsor Status
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM) Best Practice, Financial Navigation, Interview, Survey Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment Counseling, Health Education, Interview, Medical Chart Review, Monitoring, Questionnaire Administration NRG Oncology Recruiting
Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial Internet-based Intervention Wake Forest University Health Sciences Active, not recruiting
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors Best Practice, Cancer Pain Management, Educational Intervention, Electronic Health Record Review, Health Telemonitoring, Questionnaire Administration Mayo Clinic Active, not recruiting
Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Mobile Health for Adherence in Breast Cancer Patients Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention ECOG-ACRIN Cancer Research Group Active, not recruiting
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia Biospecimen Collection, Computed Tomography, Electronic Health Record Review, Medical Device Usage and Evaluation, Physical Performance Testing, Positron Emission Tomography, Survey Administration University of Rochester Recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Recruiting
IVIG for Infection Prevention After CAR-T-Cell Therapy Anti-CD19 CAR T Cells Preparation, Biospecimen Collection, Electronic Health Record Review, Immune Globulin Infusion (Human), 10% Solution, Saline, Survey Administration Fred Hutchinson Cancer Center Recruiting