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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Robertson, Gavin P.

Pennsylvania State Univ Hershey Med Ctr
United States

Targeting Aldehyde Dehydrogenase for Cancer Prevention 5R01CA241148-05
Bao, Ting

Dana-Farber Cancer Inst
United States

Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial 5R01CA251470-06 Goli Samimi, Ph.D., M.P.H.
Bao, Ting

Dana-Farber Cancer Inst
United States

Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial 5R01CA251470-06 Goli Samimi, Ph.D., M.P.H.
Bao, Ting

Dana-Farber Cancer Inst
United States

Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial 5R01CA251470-06 Goli Samimi, Ph.D., M.P.H.
Shelby, Rebecca A

Duke University
United States

Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis 5R01CA249959-05 Brennan Streck, Ph.D., RN, M.P.H.
Shelby, Rebecca A

Duke University
United States

Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis 5R01CA249959-05 Brennan Streck, Ph.D., RN, M.P.H.
Mallick, Parag Kumar

Stanford University
United States

Pathomic Predictors of Prostate Cancer Progression 5R01CA249899-05
Chen, Grace Y.

University Of Michigan At Ann Arbor
United States

Targeting cancer stem-like cells and inflammation for colon cancer chemoprevention 5R21CA273646-02
Nelson, Randy J.

West Virginia University
United States

Mechanism Underlying Sleep Disruption by Mammary Tumors 5R21CA276027-02 Marjorie Perloff, M.D.
Nelson, Randy J.

West Virginia University
United States

Mechanism Underlying Sleep Disruption by Mammary Tumors 5R21CA276027-02 Marjorie Perloff, M.D.
Schmidt, Christian Maximillian

Indiana University Indianapolis
United States

Longitudinal Proteomic and Metabolomic Predictors of Pancreatic Cyst Malignant Progression and Early Stage Pancreatic Cancer 5U01CA239522-05 Claire Zhu, Ph.D.
Godwin, Andrew K.

University Of Kansas Medical Center
United States

Extracellular Vesicle Proteomic Fingerprinting of Ovarian Cancer for Early Detection with a Nanoengineered Microsystem 5R01CA260132-05 Matthew Young, Ph.D.
Johnson, Jeremy James

University Of Illinois At Chicago
United States

Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancer 5R37CA227101-07 Amit Kumar, Ph.D.
Zhu, Yong

Univ Of Arkansas For Med Scis
United States

Explore piRNAs as a novel group of biomarkers for ovarian cancer early detection 1R21CA277412-01A1 Christos Patriotis, Ph.D., M.Sc.
Eibl, Guido Erwin Michael

University Of California Los Angeles
United States

Chemoprevention and mechanisms of obesity-promoted pancreatic adenocarcinoma 5P01CA236585-05

Clinical Trials

Status
Title Sort ascending Intervention Sponsor Status
Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer Naloxegol, Placebo, Laboratory Biomarker Analysis, Quality-of-Life Assessment Alliance for Clinical Trials in Oncology Active, not recruiting
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer Wake Forest University Health Sciences Recruiting
Mosaic Trial for Stem Cell Transplant Recipients Enhanced Usual Care (Control) Website, Intervention website Northwestern University Recruiting
Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study Best Practice, Biospecimen Collection, Endocrine Drug Therapy, Health Education, Questionnaire Administration, Symptom Specific Assessment Tool SWOG Cancer Research Network Active, not recruiting
Mobile Health for Adherence in Breast Cancer Patients Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Interview, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention ECOG-ACRIN Cancer Research Group Recruiting
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study Educational Intervention, FitBit, Goal Setting, Health Promotion and Education, Media Intervention, Telephone-Based Intervention Children's Oncology Group Active, not recruiting
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer Exercise Intervention, Methylphenidate, Placebo, Quality-of-Life Assessment, Questionnaire Administration, Stretching M.D. Anderson Cancer Center Active, not recruiting
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer metformin hydrochloride, placebo Alliance for Clinical Trials in Oncology Active, not recruiting
Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer Adaptation of IMCP for Chinese Immigrant Cancer Patients, In-depth Patient Interviews, Individual Meaning-Centered Psychotherapy for Chinese (IMCP-Ch) (For Phase 3 and Phase 4) Memorial Sloan Kettering Cancer Center Recruiting
Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors Manual Therapy M.D. Anderson Cancer Center Active, not recruiting