The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.
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About Supportive Care and Symptom Management
The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).
Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.
Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.
Selected Topics
- HEAL Initiative
- Patient Resources on Side Effects of Cancer Treatment
- Patient Resources on Coping with Cancer
Resources
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Building Bridges in Cancer Symptom Science Webinar SeriesThis series is aimed at bringing together interdisciplinary researchers in cancer symptom science to share their expertise and further discussions in the field.
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DCP Early Career Scientist Spotlight Research Seminar SeriesThis seminar series highlights nominated early career scientists who are advancing research within the areas supported by DCP.
Funding Opportunities
No matching Funding Opportunities were found.
Grantee Details
Clinical Trials
| Title Sort ascending | Intervention | Sponsor | Status |
|---|---|---|---|
| The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy) | Education control, Usual care, Yoga | Dana-Farber Cancer Institute | Active, not recruiting |
| Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer | Carboplatin, Comprehensive Geriatric Assessment, Pembrolizumab, Pemetrexed, Quality-of-Life Assessment, Questionnaire Administration | Alliance for Clinical Trials in Oncology | Active, not recruiting |
| Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy | Best Practice, Exercise Counseling, Exercise Intervention, Magnetic Resonance Imaging, Neuropathy Assessment, Questionnaire Administration | University of Rochester NCORP Research Base | Active, not recruiting |
| Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy | Best Practice, Quality-of-Life Assessment, Questionnaire Administration, Wound Dressing Material | Alliance for Clinical Trials in Oncology | Active, not recruiting |
| Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer | Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy, Intensity-Modulated Radiation Therapy, Magnetic Resonance Imaging, MnSOD Mimetic BMX-001, Placebo Administration, Questionnaire Administration | NRG Oncology | Recruiting |
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial | Laser Therapy, Quality of Life Assessment, Questionnaire Administration, Sham Intervention | Alliance for Clinical Trials in Oncology | Recruiting |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability | Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Survey Administration, Whole-Brain Radiotherapy | NRG Oncology | Recruiting |
| Telephone Support in Advanced Gastrointestinal Cancer | Acceptance and Commitment Therapy, Education/Support | Indiana University | Recruiting |
| Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer | Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration | ECOG-ACRIN Cancer Research Group | Active, not recruiting |
| Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study | Non-Interventional Study | Wake Forest University Health Sciences | Recruiting |
News and Events
Early Career Scientist Seminar - Drs. Demb and Desai
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Khurana and Harris
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Knoerl and Meisel
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Raufi and Skiba
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Shay and Yates
Date Posted: January 2, 2026