Skip to main content
An official website of the United States government

Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

View All Funding Opportunities

Grantee Details

PI Name PI Organization Title Grant Number Program Official
Winger, Joseph Giles

Duke University
United States

Engage: A Randomized Controlled Trial Testing the Efficacy of a Telehealth-Delivered Psychosocial Intervention to Decrease Symptom Interference in Patients with Advanced Cancer 5R01CA291768-02 Brennan Streck, Ph.D., RN, M.P.H.
Flynn, Kathryn E

Medical College Of Wisconsin
United States

Symptom Monitoring using Patient-Reported Outcomes to Optimize Medication Use (SyMPTOM) 5R01CA285925-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Gonzalez, Brian D

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Impact of Targeted Therapy on Cancer-Related Cognitive Impairment 5R01CA287666-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Bartolini, Francesca

Columbia University Health Sciences
United States

Investigating the Pathogenic Role of Tubulin Post-translational Modifications in CIPN 5R01CA279401-02 Rachel Altshuler, Ph.D.
Marker, Ryan J

University Of Colorado Denver
United States

Effects of a telehealth exercise program for rural cancer survivors with cancer-related fatigue including integrated longitudinal assessments of objective physical function and fatty acid oxidation 5R01CA292482-02 Goli Samimi, Ph.D., M.P.H.
Kleckner, Amber Simmons

University Of Maryland Baltimore
United States

Time-restricted eating to address cancer-related fatigue among survivors of hematological malignancies 5R01CA284082-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Kelleher, Sarah

Duke University
United States

Randomized Controlled Trial of a Hybrid-Delivered Cognitive Behavioral Symptom Management and Activity Coaching Intervention for Stem Cell Transplant Patients 5R01CA291888-02 Brennan Streck, Ph.D., RN, M.P.H.
Santomasso, Bianca Denise

Sloan-Kettering Inst Can Research
United States

Comprehensive Molecular and Clinical Characterization of Acute and Chronic Neurotoxicity Following CAR-T Cell Therapy 5R01CA293922-02 Monica Epstein, B.S.N., RN, OCN
Ligibel, Jennifer A.

Dana-Farber Cancer Inst
United States

Distance-based Exercise to preserve Function and prevENt Disability (DEFEND) 5U34CA293568-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Knoerl, Robert James

University Of Michigan At Ann Arbor
United States

Determining the Feasibility of Virtual Tailored, Music-Based Relaxation for Anxiety Among Adolescent and Young Adult Cancer Survivors. 5R34CA286712-02 Goli Samimi, Ph.D., M.P.H.
Jim, Heather S.L.

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer 5R34CA289918-02 Brennan Streck, Ph.D., RN, M.P.H.
Lehto, Rebecca H

Henry Ford Health + Michigan State University Health Sciences
United States

Support for bereaved friend and family caregivers of cancer patients 1R03CA282943-01A1 Brennan Streck, Ph.D., RN, M.P.H.
Shiozawa, Yusuke

Wake Forest University Health Sciences
United States

Contribution of cutaneous neuro-immune interactions to chemotherapy-induced peripheral neuropathy 5R21CA297068-02 Rachel Altshuler, Ph.D.
Justilien, Verline

Mayo Clinic Jacksonville
United States

ECT2 Isoform Switch in Pancreatic Cancer. 5R21CA296671-02 Matthew Young, Ph.D.

Clinical Trials

Status
Title Intervention Sponsor Status Sort descending
Wellness App for Sleep Disturbance in Hematological Cancer Patients Wellness app intervention #1, Wellness app intervention #2 The University of Texas Health Science Center at San Antonio Active, not recruiting
Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial Internet-based Intervention Wake Forest University Health Sciences Active, not recruiting
A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources Internet-Based Intervention - CONNECT, Patient Navigation, Support for Caregiver - Generic List, Support for Caregiver - Personalized List Wake Forest University Health Sciences Active, not recruiting
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy) Education control, Usual care, Yoga Dana-Farber Cancer Institute Active, not recruiting
Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices Non-Interventional Wake Forest University Health Sciences Enrolling by invitation
Understanding Needs of Older Patients Prior to Starting Cancer Treatment Assessment, Educational Intervention, Electronic Health Record Review, Internet-Based Intervention, Interview, Survey Administration Wake Forest University Health Sciences Enrolling by invitation
A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial Electronic Health Record Review, Interview, Support, Survey Administration Fred Hutchinson Cancer Center Not yet recruiting
New Assessment System in Measuring Symptom Distress in Cancer Patients Interview, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Recruiting
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer Wake Forest University Health Sciences Recruiting
Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials Questionnaires Eastern Cooperative Oncology Group Recruiting