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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Santomasso, Bianca Denise

Sloan-Kettering Inst Can Research
United States

Comprehensive Molecular and Clinical Characterization of Acute and Chronic Neurotoxicity Following CAR-T Cell Therapy 5R01CA293922-02 Monica Epstein, B.S.N., RN, OCN
Ligibel, Jennifer A.

Dana-Farber Cancer Inst
United States

Distance-based Exercise to preserve Function and prevENt Disability (DEFEND) 5U34CA293568-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Knoerl, Robert James

University Of Michigan At Ann Arbor
United States

Determining the Feasibility of Virtual Tailored, Music-Based Relaxation for Anxiety Among Adolescent and Young Adult Cancer Survivors. 5R34CA286712-02 Goli Samimi, Ph.D., M.P.H.
Jim, Heather S.L.

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer 5R34CA289918-02 Brennan Streck, Ph.D., RN, M.P.H.
Shiozawa, Yusuke

Wake Forest University Health Sciences
United States

Contribution of cutaneous neuro-immune interactions to chemotherapy-induced peripheral neuropathy 5R21CA297068-02 Rachel Altshuler, Ph.D.
Justilien, Verline

Mayo Clinic Jacksonville
United States

ECT2 Isoform Switch in Pancreatic Cancer. 5R21CA296671-02 Matthew Young, Ph.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Inhibition of NLRP3 inflammasome for the treatment of Chemotherapy-induced peripheral neuropathy 5R21CA296516-02 Rachel Altshuler, Ph.D.
Grossman, Douglas

Utah State Higher Education System--University Of Utah
United States

Electrical impedance dermography as a biomarker for basal and squamous cell carcinoma 5R21CA289101-02 Nicholas Hodges, Ph.D.
Ah, Diane Marie Von

Ohio State University
United States

Cognitive Training for Cancer-related Cognitive Impairment: A Multi-Center Randomized Controlled Trial 5R01CA276222-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Kang, Dongkyun

University Of Arizona
United States

Non-invasive, quantitative microscopic biomarkers for chemotherapy-induced peripheral neuropathy 1R01CA301271-01 Rachel Altshuler, Ph.D.
Clare, Susan E.

Northwestern University At Chicago
United States

Lipid-initiated epigenetic reprogramming of the breast to a neural phenotype 5R21CA288676-02 John Clifford, Ph.D.
Pistilli, Emidio Edward

West Virginia University
United States

Targeting Muscle Fatigability During Cachexia 5R01AR079445-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Eisenmann, Eric Daniel

Ohio State University
United States

Damage-associated molecular patterns in chemotherapy toxicity 1R37CA299879-01 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Intervention Sponsor Sort descending Status
A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial Electronic Health Record Review, Interview, Support, Survey Administration Fred Hutchinson Cancer Center Recruiting
The MIND-BC Study: MIND Diet for Breast Cancer Cognition MIND Diet, Usual Diet H. Lee Moffitt Cancer Center and Research Institute Recruiting
Telephone Support in Advanced Gastrointestinal Cancer Acceptance and Commitment Therapy, Education/Support Indiana University Recruiting
Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors Biospecimen Collection, Fisetin, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting
New Assessment System in Measuring Symptom Distress in Cancer Patients Interview, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Recruiting
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors Manual Therapy M.D. Anderson Cancer Center Active, not recruiting
Controlled Trial Of Acupuncture To Prevent Radiation-Induced Xerostomia Acupuncture - Group 1, Acupuncture - Group 2, Questionnaire, Standard Care M.D. Anderson Cancer Center Active, not recruiting