Skip to main content
An official website of the United States government

Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

View All Funding Opportunities

Grantee Details

PI Name PI Organization Title Grant Number Program Official
Goode, Diana J

University Of New England
United States

Novel expression of MHC class II on DRG neurons and its role in promoting antinociceptive CD4+ T cells in females during chemotherapy-induced peripheral neuropathy 5R01CA267554-04 Rachel Altshuler, Ph.D.
Johnson, Constance Margaret

University Of Texas Hlth Sci Ctr Houston
United States

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy 3R01CA245054-05S1 Rachel Altshuler, Ph.D.
Melemedjian, Ohannes Kevork

University Of Maryland Baltimore
United States

Identification of novel targets for the treatment of chemotherapy-induced painful peripheral neuropathy 4R01CA249939-02 Rachel Altshuler, Ph.D.
Brown, Austin L

Baylor College Of Medicine
United States

A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia 5R01CA272981-03 Rachel Altshuler, Ph.D.
Mclouth, Laurie

University Of Kentucky
United States

Pathways, a Hope-Based Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life during Advanced Lung Cancer Treatment 5R01CA283929-03 Brennan Streck, Ph.D., RN, M.P.H.
Damaj, M. Imad

Virginia Commonwealth University
United States

Targeting Sphingosine-1-phosphate (S1P1) receptors for the treatment of Aromatase Inhibitors-induced Musculoskeletal Symptoms 5R01CA272147-03 Rachel Altshuler, Ph.D.
Fuschiotti, Patrizia

University Of Pittsburgh At Pittsburgh
United States

Develop IL13Ra1 for diagnosis of early-stage mycosis fungoides 5R21CA280445-02 Wendy Wang, Ph.D., M.Sc.
Phillips, Nicholas S

St. Jude Children'S Research Hospital
United States

Cardiopulmonary function and cerebral blood flow in Hodgkin Lymphoma survivors 5R21CA280230-02 Eileen Dimond, R.N., M.S.
Staff, Nathan P

Mayo Clinic Rochester
United States

Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity 5R01CA275870-03 Rachel Altshuler, Ph.D.
Garcia, Jose M.

Seattle Inst For Biomedical/Clinical Res
United States

SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) 5R01CA279220-02 Marjorie Perloff, M.D.
Mehrara, Babak J

Sloan-Kettering Inst Can Research
United States

Mechanisms of racial disparity in breast cancer-related lymphedema 5R01CA278599-03
Xiao, Yi

University Of Tx Md Anderson Can Ctr
United States

Exploring new strategy for breast cancer immunoprevention by targeting histamine receptor H1 5R21CA286318-02 Anda Vlad, M.D., Ph.D.
Deng, Gary E

University Of California-Irvine
United States

Acupuncture to Improve Outcomes in Patients with Sepsis: a Randomized Controlled Trial 7R21CA286330-03 Goli Samimi, Ph.D., M.P.H.
Pozdeyev, Nikita

University Of Colorado Denver
United States

Genetic architecture of thyroid cancer and its clinical utility 5R21CA282380-02 Wendy Wang, Ph.D., M.Sc.
Webster, Nicholas J

Veterans Medical Research Fdn/San Diego
United States

The Effect of Time-Restricted Eating on the Efficiency of Chemo- and Hormonal-Therapy in Breast Cancer 5R21CA288777-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND

Clinical Trials

Status
Title Intervention Sort descending Sponsor Status
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia Best Practice, Biospecimen Collection, Cytarabine, Electronic Health Record Review, Placebo Administration, Xylitol-containing Oral Wipe Children's Oncology Group Not yet recruiting
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer Best Practice, Biospecimen Collection, Electronic Health Record Review, Survey Administration, Triptorelin Pamoate Children's Oncology Group Recruiting
Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study Best Practice, Biospecimen Collection, Endocrine Drug Therapy, Health Education, Questionnaire Administration, Symptom Specific Assessment Tool SWOG Cancer Research Network Active, not recruiting
Cancer and Blood Pressure Management, CARISMA Study Best Practice, Blood Pressure Measurement, Clinical Management, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors (ASCENT) Best Practice, Cancer Pain Management, Educational Intervention, Electronic Health Record Review, Health Telemonitoring, Questionnaire Administration Mayo Clinic Recruiting
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial Best Practice, Comprehensive Geriatric Assessment, Educational Intervention, Exercise Intervention, Questionnaire Administration, Tailored Intervention University of Rochester Recruiting
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy Best Practice, Educational Intervention, Motivational Interviewing, Quality-of-Life Assessment, Questionnaire Administration, Text Message-based Navigation Intervention Alliance for Clinical Trials in Oncology Active, not recruiting
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy Best Practice, Exercise Counseling, Exercise Intervention, Magnetic Resonance Imaging, Neuropathy Assessment, Questionnaire Administration University of Rochester NCORP Research Base Active, not recruiting
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM) Best Practice, Financial Navigation, Interview, Survey Administration ECOG-ACRIN Cancer Research Group Recruiting
A Text-based Intervention in Improving Adherence to Hormone Therapy in Patients With Stage I-III Hormone Receptor Positive Breast Cancer Best Practice, Focus Group, Questionnaire Administration, Text Message Thomas Jefferson University Active, not recruiting