By Stuart G. Baker, 2017
Introduction
This software computes meta-analysis and extrapolation estimates for an instrumental variable meta-analysis of randomized trial or before-and-after studies (the latter also known as the paired availability design). The software also checks on the assumptions if sufficient data are available.
References
Baker SG and Lindeman KL Revisiting a discrepant result: a propensity score analysis, the paired availability design for historical controls, and a meta-analysis of randomized trials, Journal of Causal Inference 2013; 1:51–82; correction 2014:113.
Requirement: Mathematica Version 11 or later
To run the program
| copy | all files into some folder called "FOLDER" |
|---|---|
| start | a new Mathematica session |
| type | SetDirectory["FOLDER"] |
| type | <<pfit.m |
| type initially to generate symbolic results | PFit[dataset, options] |
Key Function: PFit[dataset] where
dataset={data, names of studies, name of data set, label for x-axis, label for y-axis}
data={n0,e0,c00,c01,c0,n1,e1,c10,c11,c1},
with -1 denoting a missing value for c00, c01,c10,c11
| n0 | Number in group 0 (control or before group) |
|---|---|
| e0 | Number receiving treatment in group 0 |
| c00 | Number in group 0 receiving no treatment with outcome 1 |
| c01 | Number in group 0 receiving treatment with outcome 1 |
| c0 | Number in group 0 with outcome 0 |
| n1 | Number in group 1 (experimental or after group) |
| e1 | Number receiving treatment in group 1 |
| c10 | Number in group 1 receiving no treatment with outcome 1 |
| c11 | Number in group 1 receiving treatment with outcome 1 |
| c1 | Number in group 1 with outcome 1 |
| Option | Default | Explanation |
|---|---|---|
| ShowTables | False | Prints table of data and table of basic estimates |
| ShowExtrapolation | False | Plots extrapolation estimates using regression models |
File Contents
Download All (ZIP, 10 KB)
| pfit.m | main package |
|---|---|
| pfitmeta | meta-analysis |
| pfitreg | regression extrapolation |
| pfitplot | plotting function |
| pfitdata | data for epidural analgesia example |
Disclaimer
This code is provided "as is", without warranty of any kind, express or implied, including but not limited to the warranties of merchantability, fitness for a particular purpose and non-infringement. In no event shall the NCI or the individual developers be liable for any claim, damages or other liability of any kind. Use of this code by recipient is at recipient's own risk. NCI makes no representations that the use of the code will not infringe any patent or proprietary rights of third parties.
Last updated: April 30, 2018