2019 News Articles

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Taking Advantage of the Transportation Processes from Inside to Outside the Cell to Detect Cancer

As cancer researchers delve into the many molecular processes that guide cell life within the body, NCI is looking for ways to characterize and measure different substances in this process, with an eye to identifying who has... Read More

POSTED: 12/11/2019

Parts of a cell, displaying where an extracellular viscile forming.

RESEARCH UPDATE: ON THE CLINICAL FRONT Selectively Inhibitory Effects of Green Tea Polyphenols on Microbial Metabolism The bioavailability of green tea polyphenols (GTP) is limited and unabsorbed GTP can have bi-... Read More

POSTED: 10/23/2019

A cup of green tea.

TMIST Ramps Up to Illuminate Breast Cancer Screening

TMIST (Tomosynthesis Mammographic Imaging Screening Trial), the large NCI screening study to learn about the best ways to find breast cancer in women who have no symptoms, is ramping up with 16,505 participants enrolled to... Read More

POSTED: 10/17/2019

Photo of Worta McCaskill-Stevens and Etta Pisano

Study Quantifies Impact of NCI-sponsored Trials on Clinical Cancer Care

A new study shows that nearly half of phase 3 cancer clinical trials carried out by the National Cancer Institute (NCI)-sponsored SWOG Cancer Research Network, one of five groups in NCI’s National Clinical Trials Network (... Read More

POSTED: 09/18/2019

45% of 182 Phase 3 clinical trials between 1980 and 2017 incluenced guideline care or new drug approvals.

Michigan’s Philip Stella receives NCORP 2019 Harry Hynes Award: Conversation with the Cancer Letter

Philip J. Stella, the principal investigator of the Michigan Cancer Research Consortium NCI Community Oncology Research Program site in Ann Arbor, won the 2019 Harry Hynes Award.  The award is given annually to NCORP PIs... Read More

POSTED: 09/13/2019

Portrait of Philip J. Stella, MD

NCI Annual Plan & Budget Proposal for Fiscal Year 2021

The year 2021 will mark the 50th anniversary of the National Cancer Act of 1971, the landmark legislation that intensified support for cancer research in the United States. The investment sparked a biomedical revolution... Read More

POSTED: 09/05/2019

Cancer Continuum: Understanding, Preventing, Detecting & Diagnosis, Treating, Advancing.

The National Cancer Institute (NCI) has awarded 53 grants to researchers in the NCI Community Oncology Research Program (NCORP) to conduct multi-site cancer clinical trials and cancer care delivery studies in their... Read More

POSTED: 08/19/2019

Video still of Cancer Clinical Trials in Your Community

Study Suggests Reviewing Lung Cancer Screening Criteria for African Americans

Clinical recommendations on who should be screened for lung cancer are based largely on how long a person smoked and the number of cigarettes they smoked. But current recommendations may need to be reviewed when it comes to... Read More

POSTED: 07/31/2019

African American patient pictured with a nurse during a lung cancer screening procedure.

RESEARCH UPDATE: ON THE CLINICAL FRONT Vitamin D Supplements and Prevention of Cancer: the Vitamin D and Omega-3 Trial (VITAL) Observational studies suggest that lower vitamin D levels are associated with a higher cancer... Read More

POSTED: 07/25/2019

A display of foods containing vitamin D3 and omega-3 fatty acids.

Why I choose to play a dual role in TMIST

By Worta McCaskill-Stevens As a physician-scientist, I have spent my career advancing research in women’s health. I was a part of the planning effort to design and launch TMIST—the Tomosynthesis Mammographic Imaging... Read More

POSTED: 05/24/2019

Portrait of Worta McCaskill-Stevens

A new video from the National Cancer Institute (NCI) highlights the research efforts of the NCI Community Oncology Research Program (NCORP) in implementing cancer clinical trials and other research studies across the country... Read More

POSTED: 05/16/2019

Title still of the NCORP video entitled, 'Cancer Clinical Trials in Your Community".

Prostate Cancer Prevention and Finasteride: A Conversation with NCI’s Dr. Howard Parnes

In 2003, results from the Prostate Cancer Prevention Trial (PCPT)—an NCI-funded randomized clinical trial with nearly 19,000 participants—showed that men aged 55 and older who used the drug finasteride daily for 7 years had... Read More

POSTED: 05/13/2019

Portrait of Howard Parnes, PhD

RESEARCH UPDATE: ON THE CLINICAL FRONT Caffeinated Coffee and Tea and the Risk of Non-Melanoma Skin Cancer Among Chinese Coffee and tea are the most widely consumed beverages in the world and epidemiological evidence... Read More

POSTED: 04/29/2019

Cups of coffee.

Could a Vaccine Prevent Colorectal Cancer in People with Lynch Syndrome?

Researchers have taken the first steps toward developing a vaccine to prevent cancer in people with Lynch syndrome, an inherited condition that elevates a person’s risk of colorectal, endometrial, and other types of cancer.... Read More

POSTED: 04/19/2019

An immune cell (pink and red) attacks a tumor cell (blue) that makes neoantigens (blue and orange). A vaccine could help train immune cells to recognize neoantigens.

TMIST PI Pisano: “Are we further reducing breast cancer mortality the more intensively we screen?”

The Tomosynthesis Mammographic Imaging Screening Trial, a massive randomized trial of early detection, is asking an important question:  Is digital breast tomosynthesis better than digital mammography in reducing development... Read More

POSTED: 03/19/2019

Portrait of Etta Pisano, MD

NCI participated in the American Association for Cancer Research (AACR) Annual Meeting, held March 29–April 3, 2019, at Georgia World Congress Center in Atlanta, GA, including presenting the following research results from... Read More

POSTED: 03/15/2019

At 12 NCI Community Oncology Research Program (NCORP) sites across the United States, a new kind of study will soon be opening for patients with advanced malignancies being treated with molecularly targeted therapies. The... Read More

POSTED: 03/01/2019

Image of a DNA double helix

After Lung Cancer Screening, Follow-Up Procedures May Be Riskier than Thought

Being screened for lung cancer can lead to follow-up diagnostic procedures, including invasive ones. The risk of complications from those invasive procedures may be higher than previously thought, a new study suggests. By... Read More

POSTED: 02/08/2019

A person being screened for lung cancer with a low-dose CT scan.

RESEARCH UPDATE: ON THE CLINICAL FRONT Circulating Bile Acids in Response to a Whole vs Refined Grain Dietary Pattern in Healthy Adults Little is known about circulating plasma bile acid concentrations and their capacity... Read More

POSTED: 01/24/2019

Image of foods high in whole grains, legumes, and fruits and vegetables.

FHP Health Center in Guam was approved in January as the newest affiliate of the National Cancer Institute Community Oncology Research Program (NCORP) to bring cancer clinical trials and cancer care delivery studies to... Read More

POSTED: 01/24/2019

University of Hawaii Cancer Center Minority/Underserved NCORP team visiting FHP Health Center-Guam

Managing Cancer Pain: Are Better Approaches on the Horizon?

Pain is a common and much-feared symptom among people being treated for cancer and long-term survivors. Cancer pain can be caused by the disease itself, its treatments, or a combination of the two. It may be short-lived or... Read More

POSTED: 01/23/2019

  Sensory nerve fibers (red) sprouting into prostate tumor cells (green) that have metastasized to the bone. Credit: Patrick Mantyh, PhD, JD, University of Arizona

The Final Verdict on Finasteride

Finasteride, a generic hormone-blocking drug, was found to reduce the risk of prostate cancer by 25 percent in the landmark Prostate Cancer Prevention Trial (PCPT). Long- term data, published today in the New England Journal... Read More

POSTED: 01/23/2019

Hepatitis Goes Undiagnosed in Cancer Patients

Results from the largest study of hepatitis B and C and HIV infection prevalence in cancer patients show that an alarmingly high rate of undiagnosed acute and chronic hepatitis B and C. Hepatitis B and C are serious but... Read More

POSTED: 01/17/2019

Portrait of Scott Ramsey, MD, PhD

For Early-Stage Lung Cancer, Study Identifies Potential New Biomarker, Treatment Target

A new study has identified a potential biomarker of early-stage non–small cell lung cancer (NSCLC). The biomarker could help diagnose precancerous lung growths (called nodules or lesions) and early-stage lung cancers... Read More

POSTED: 01/03/2019

Imaging scans identified a lung nodule (panels A and B) which, over the course of 11 months progressed (panels C and D) and, following a biopsy, was confirmed as lung cancer.