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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name PI Organization Title Grant Number Program Official Sort descending
Storz, Peter

Mayo Clinic Jacksonville
United States

Deiminated molecules as markers for developing pancreatic cancer - A1 5R21CA279916-02 Matthew Young, Ph.D.
Grossman, Douglas

Utah State Higher Education System--University Of Utah
United States

Electrical impedance dermography as a biomarker for basal and squamous cell carcinoma 5R21CA289101-02 Nicholas Hodges, Ph.D.
Bryan, Angela

University Of Colorado
United States

Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC 5R01CA284860-03 Brennan Streck, Ph.D., RN, M.P.H.
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Mclouth, Laurie

University Of Kentucky
United States

Pathways, a Hope-Based Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life during Advanced Lung Cancer Treatment 5R01CA283929-03 Brennan Streck, Ph.D., RN, M.P.H.
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Mosaic: RCT of a Digital Health Intervention Delivering Peer Support Narratives and Psychoeducation to English- and Spanish-Speaking Stem Cell Transplant Recipients 5R01CA292116-02 Brennan Streck, Ph.D., RN, M.P.H.
Winger, Joseph Giles

Duke University
United States

Engage: A Randomized Controlled Trial Testing the Efficacy of a Telehealth-Delivered Psychosocial Intervention to Decrease Symptom Interference in Patients with Advanced Cancer 5R01CA291768-02 Brennan Streck, Ph.D., RN, M.P.H.
Duvall, Adam S.

University Of Chicago
United States

Tailoring a fun and engaging tech-assisted cognitive behavioral therapy program for adolescents and young adults with hematological malignancies: A planning grant 1R34CA297498-01 Brennan Streck, Ph.D., RN, M.P.H.
Washington, Karla

Washington University
United States

Problem-Solving Therapy for Cancer Caregivers: A Randomized Clinical Trial in Outpatient Palliative Care 5R01CA258311-05 Brennan Streck, Ph.D., RN, M.P.H.
Kelleher, Sarah

Duke University
United States

Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings 5R21CA273832-02 Brennan Streck, Ph.D., RN, M.P.H.
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Im, Eun-Ok

University Of Texas At Austin
United States

Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors 5R33CA280979-04 Brennan Streck, Ph.D., RN, M.P.H.
Wang, Jing

New York University School Of Medicine
United States

Optimizing the use of ketamine to reduce chronic postsurgical pain 3UH3CA261067-05S1 Brennan Streck, Ph.D., RN, M.P.H.
John, Esther M.

Stanford University
United States

Stress, inflammation, and health-related quality of life of long-term breast cancer survivors 1R21CA290430-01 Brennan Streck, Ph.D., RN, M.P.H.

Clinical Trials

Status
Title Intervention Sponsor Status
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia Laboratory Biomarker Analysis, Simplified Patient Care Strategy ECOG-ACRIN Cancer Research Group Active, not recruiting
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment Children's Oncology Group Recruiting
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer Conization, Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Conventional Surgery, Therapeutic Lymphadenectomy GOG Foundation Active, not recruiting
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study Non-Interventional Study Wake Forest University Health Sciences Recruiting
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Telephone Support in Advanced Gastrointestinal Cancer Acceptance and Commitment Therapy, Education/Support Indiana University Recruiting