Trial NCT04939090

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

This phase III trial compares the effects of olanzapine versus megestrol acetate in treating
loss of appetite in patients with cancer that has spread to other places in the body
(advanced). Olanzapine may stimulate and increase appetite. This study aims to find out if
olanzapine is better than the usual approach (megestrol acetate) for stimulating appetite and
preventing weight loss.


Megestrol Acetate, Olanzapine, Questionnaire Administration


Advanced Malignant Solid Neoplasm, Anorexia, Hematopoietic and Lymphoid Cell Neoplasm


Aminah Jatoi, MD, Debra M. Prow, Bryan A. Faller, Kendrith M. Rowland, Deborah W. Wilbur, Joshua Lukenbill, Grant R. Seeger, Ki Y. Chung, Nicholas DiBella, Isoken Koko, Richard L. Deming, Tareq Al Baghdadi, Preston D. Steen, Jay W. Carlson

See list of participating sites