Trial NCT03196180

Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

This phase I clinical trial studies the side effects of topical fluorouracil and imiquimod
ointment in treating patients with high-grade cervical intraepithelial neoplasia. Topical
fluorouracil may kill precancerous cells. Imiquimod ointment may stimulate the immune system.
Applying topical fluorouracil and imiquimod ointment may cause fewer side effects and may be
a better way to treat patients with precancerous cervical lesions.

Intervention

Imiquimod, Laboratory Biomarker Analysis, Topical Fluorouracil

Condition

High Grade Cervical Intraepithelial Neoplasia, p16 Positive Neoplastic Cells Present

Investigators

Lisa Rahangdale

See list of participating sites