Management of Tobacco Treatment Intervention in Reducing Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes

This randomized phase III trial studies how well management of a tobacco treatment
intervention works in reducing surgical complications in patients with newly diagnosed lung
cancer who smoke cigarettes. Management of a tobacco treatment intervention compares
varenicline (a drug that reduces the craving and withdrawal symptoms that occur with
abstinence from nicotine) and behavioral interventions (consisting of a brief
clinician-delivered intervention and tobacco quitline [tobacco cessation service available
through a toll-free telephone number] follow-up) with placebo (a pill with no active
medication) along with similar behavioral interventions. It is not yet known whether
management of a tobacco treatment intervention is more effective in reducing surgical
complications than placebo.


Varenicline, Placebo, Tobacco Cessation Counseling


Lung Carcinoma


Ivana Croghan, PhD

See list of participating sites