Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

This randomized phase III trial studies whether changes in diet and physical activity can
increase the length of survival without the return of cancer (progression-free survival)
compared with usual care in patients with previously treated stage II, III, or IV ovarian,
fallopian tube, or primary peritoneal cancer. A healthy diet and physical activity program
and counseling may help patients make healthier lifestyle choices. It is not yet known
whether changes in diet and exercise may help increase progression-free survival in patients
with previously treated cancer.

Intervention

Behavioral Dietary Intervention, Compliance Monitoring, Counseling, Educational Intervention, Exercise Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration

Condition

Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Malignant Ovarian Brenner Tumor, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mucinous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Adenocarcinoma, Ovarian Transitional Cell Carcinoma, Primary Peritoneal Serous Adenocarcinoma, Stage IIA Fallopian Tube Cancer AJCC v6 and v7, Stage IIA Ovarian Cancer AJCC V6 and v7, Stage IIB Fallopian Tube Cancer AJCC v6 and v7, Stage IIB Ovarian Cancer AJCC v6 and v7, Stage IIC Fallopian Tube Cancer AJCC v6 and v7, Stage IIC Ovarian Cancer AJCC v6 and v7, Stage IIIA Fallopian Tube Cancer AJCC v7, Stage IIIA Ovarian Cancer AJCC v6 and v7, Stage IIIA Primary Peritoneal Cancer AJCC v7, Stage IIIB Fallopian Tube Cancer AJCC v7, Stage IIIB Ovarian Cancer AJCC v6 and v7, Stage IIIB Primary Peritoneal Cancer AJCC v7, Stage IIIC Fallopian Tube Cancer AJCC v7, Stage IIIC Ovarian Cancer AJCC v6 and v7, Stage IIIC Primary Peritoneal Cancer AJCC v7, Stage IV Fallopian Tube Cancer AJCC v6 and v7, Stage IV Ovarian Cancer AJCC v6 and v7, Stage IV Primary Peritoneal Cancer AJCC v7, Undifferentiated Fallopian Tube Carcinoma, Undifferentiated Ovarian Carcinoma

Investigators

David Alberts, Linda Van Le, Benjamin B. Bridges, Keren Sturtz, Mehmet S. Copur, John P. Kuebler, Maria T. Grosse-Perdekamp, Jessica A. Thomes Pepin, Paul E. Berard, Michael E. Carney, Shaker R. Dakhil, John M. McDonald, J. R. Liu, Mark E. Borowsky, Peter G. Rose, James L. Wade, Elizabeth L. Dickson Michelson, Philip J. Stella, Veena S. John, Heidi J. Gray, Timothy J. Vanderkwaak, Leslie R. DeMars, Thomas C. Krivak, Joshua S. Trinidad, Maria C. Bell, Michael J. Callahan, Guilherme Henrique C. Cantuaria, Paul Celano, David P. Warshal, Eva Chalas, John A. Keech, David G. Mutch, William E. Richards, Saketh R. Guntupalli, Stacy D. D'Andre, David M. O'Malley, Alexander B. Olawaiye, Laura J. Havrilesky, Young B. Kim, Sharad A. Ghamande, Jeffrey W. Elder, Bobbie J. Rimel, Radhika P. Gogoi, Robin Farias-Eisner, David M. Kushner, Kathleen J. Yost, Matthew L. Ryan, Craig R. Nichols, Jay W. Carlson, Anthony C. Evans, William H. Bradley, Benjamin T. Marchello, Babak Edraki, Sarah M. Temkin, Frederick R. Ueland, John K. Chan, Theresa L. Werner, Christopher J. Darus, Andrea D. Jewell, Vinay K. Gudena, Joseph W. Leach, Carlton L. Schwab, Jonathan E. Tammela, Jack B. Basil, Mihaela C. Cristea, Elena S. Ratner, Robert A. Burger, Janiel M. Cragun, Randolph B. Deger, Shohreh Shahabi, Michael T. McHale, Robert S. Mannel, John W. Byron, Michael P. Hopkins, Timothy D. Moore, William E. Luginbuhl, Peter C. Morris, Donald P. Seago, Warner K. Huh, James V. Fiorica, Michael L. Berman, James E. Kendrick, Whitney S. Graybill, Caela R. Miller, Mark A. Miller, Summer B. Dewdney, Paul A. DiSilvestro, Aparna A. Kamat, Michael W. Method, Michael P. Stany, Michael L. Pearl, Karen H. Lu, Scott E. Lentz, Jamie L. Lesnock, M. G. Fort, Chad A. Hamilton, Larry C. Kilgore, Mary J. Cunningham, John H. Farley, Alcee J. Jumonville, Molly A. Brewer, Nicola M. Spirtos, Nicholas P. Taylor, John W. Moroney, Jeanne M. Schilder, Mark S. Shahin, Susanna Hong, Andrew S. Camarata, Janet L. Osborne, Rakesh Gaur, Kristin K. Zorn, Sudarshan K. Sharma, Susan C. Modesitt, Corrine L. Zarwan, Diana C. Medgyesy, Henry L. Sonneborn

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