Publication Results

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Metastatic prostate cancer at diagnosis and through progression in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Pinsky PF,  Black A,  Daugherty SE,  Hoover R,  Parnes H,  Smith ZL,  Eggener S,  Andriole GL,  Berndt SI
Cancer 2019 Sep 1;125(17):2965-2974
Major Program(s) or Research Group(s): Early DetectionProstate and Urologic Cancer
PubMed ID: 31067347
PMC ID: PMC6690759 [available on September 01, 2020]

Overall mortality in men and women in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Pinsky PF,  Miller EA,  Zhu CS,  Prorok PC
J Med Screen 2019 Sep;26(3):127-134
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 30943843
PMC ID: not available

Extended follow-up for prostate cancer incidence and mortality among participants in the Prostate, Lung, Colorectal and Ovarian randomized cancer screening trial.

Pinsky PF,  Miller E,  Prorok P,  Grubb R,  Crawford ED,  Andriole G
BJU Int 2019 May;123(5):854-860
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30288918
PMC ID: PMC6450783

Lung Cancer Screening Benefits and Harms Stratified by Patient Risk: Information to Improve Patient Decision Aids.

Bellinger C,  Pinsky P,  Foley K,  Case D,  Dharod A,  Miller D
Ann Am Thorac Soc 2019 Apr;16(4):512-514
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30620619
PMC ID: PMC6943875

Association of Nonadherence to Cancer Screening Examinations With Mortality From Unrelated Causes: A Secondary Analysis of the PLCO Cancer Screening Trial.

Pierre-Victor D,  Pinsky PF
JAMA Intern Med 2019 Feb 1;179(2):196-203
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30592477
PMC ID: PMC6439655

Correction to: The relationship between diabetes, prostate-specific antigen screening tests, and prostate cancer.

Miller EA,  Pinsky PF,  Pierre-Victor D
Cancer Causes Control 2019 Feb;30(2):215-216
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 30506128
PMC ID: not available

Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: long-term follow-up of the randomised US PLCO cancer screening trial.

Miller EA,  Pinsky PF,  Schoen RE,  Prorok PC,  Church TR
Lancet Gastroenterol Hepatol 2019 Feb;4(2):101-110
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30502933
PMC ID: PMC6335177

Characteristics and Outcomes of Small Cell Lung Cancer Detected by CT Screening.

Thomas A,  Pattanayak P,  Szabo E,  Pinsky P
Chest 2018 Dec;154(6):1284-1290
Major Program(s) or Research Group(s): Early DetectionLung and Upper Aerodigestive Cancer
PubMed ID: 30080997
PMC ID: PMC6335258

The relationship between diabetes, prostate-specific antigen screening tests, and prostate cancer.

Miller EA,  Pinsky PF,  Pierre-Victor D
Cancer Causes Control 2018 Oct;29(10):907-914
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30094676
PMC ID: not available

Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening.

Pinsky PF,  Loberg M,  Senore C,  Wooldrage K,  Atkin W,  Bretthauer M,  Cross AJ,  Hoff G,  Holme O,  Kalager M,  Segnan N,  Schoen RE
Gastroenterology 2018 Oct;155(4):1059-1068.e2
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29935150
PMC ID: not available

Power of a Trial Investigating a Low-Intensity PSA-Based Screening Intervention.

Pinsky PF
JAMA 2018 Aug 14;320(6):600
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30120468
PMC ID: not available

Secondary prostate cancer screening outcomes by race in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Screening Trial.

Miller EA,  Pinsky PF,  Black A,  Andriole GL,  Pierre-Victor D
Prostate 2018 Aug;78(11):830-838
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29667217
PMC ID: not available

The IARC Perspective on Colorectal Cancer Screening.

Pinsky P,  Rabeneck L,  Lauby-Secretan B
N Engl J Med 2018 Jul 19;379(3):301-302
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30021099
PMC ID: not available

Lung cancer screening with low-dose CT: a world-wide view.

Pinsky PF
Transl Lung Cancer Res 2018 Jun;7(3):234-242
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30050762
PMC ID: PMC6037972

False-positive screens and lung cancer risk in the National Lung Screening Trial: Implications for shared decision-making.

Pinsky PF,  Bellinger CR,  Miller DP Jr
J Med Screen 2018 Jun;25(2):110-112
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28929865
PMC ID: not available

Use of raloxifene and tamoxifen by breast cancer risk level in a Medicare-eligible cohort.

Pinsky PF,  Miller E,  Heckman-Stoddard B,  Minasian L
Am J Obstet Gynecol 2018 Jun;218(6):606.e1-606.e9
Major Program(s) or Research Group(s): Breast and Gynecologic CancerEarly Detection ;  Office of the Director
PubMed ID: 29630889
PMC ID: PMC5970073

Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence.

Click B,  Pinsky PF,  Hickey T,  Doroudi M,  Schoen RE
JAMA 2018 May 15;319(19):2021-2031
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29800214
PMC ID: PMC6583246

Comment on "Systematic review and meta-analysis by Dube et al."

Pinsky PF
Am J Gastroenterol 2018 May;113(5):780-781
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29453379
PMC ID: not available

Does the evidence support the implementation of lung cancer screening with low-dose computed tomography?

Pinsky PF
Expert Rev Respir Med 2018 Apr;12(4):257-260
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29338501
PMC ID: not available

The efficacy of prostate-specific antigen screening: Impact of key components in the ERSPC and PLCO trials.

de Koning HJ,  Gulati R,  Moss SM,  Hugosson J,  Pinsky PF,  Berg CD,  Auvinen A,  Andriole GL,  Roobol MJ,  Crawford ED,  Nelen V,  Kwiatkowski M,  Zappa M,  Luján M,  Villers A,  de Carvalho TM,  Feuer EJ,  Tsodikov A,  Mariotto AB,  Heijnsdijk EAM,  Etzioni R
Cancer 2018 Mar 15;124(6):1197-1206
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29211316
PMC ID: PMC5839977

Early detection versus primary prevention in the PLCO flexible sigmoidoscopy screening trial: Which has the greatest impact on mortality?

Doroudi M,  Schoen RE,  Pinsky PF
Cancer 2017 Dec 15;123(24):4815-4822
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 28976536
PMC ID: PMC5716922

The bimanual ovarian palpation examination in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: Performance and complications.

Doroudi M,  Kramer BS,  Pinsky PF
J Med Screen 2017 Dec;24(4):220-222
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection ;  Office of the Director
PubMed ID: 27903809
PMC ID: not available

The relationship of cancer characteristics and patient outcome with time to lung cancer diagnosis after an abnormal screening CT.

Sonavane SK,  Pinsky P,  Watts J Jr,  Gierada DS,  Munden R,  Singh SP,  Nath H
Eur Radiol 2017 Dec;27(12):5113-5118
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28616728
PMC ID: not available

Outcomes from ovarian cancer screening in the PLCO trial: Histologic heterogeneity impacts detection, overdiagnosis and survival.

Temkin SM,  Miller EA,  Samimi G,  Berg CD,  Pinsky P,  Minasian L
Eur J Cancer 2017 Dec;87:182-188
Major Program(s) or Research Group(s): Breast and Gynecologic CancerEarly Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29156299
PMC ID: not available

Lung Cancer Risk Associated With New Solid Nodules in the National Lung Screening Trial.

Pinsky PF,  Gierada DS,  Nath PH,  Munden R
AJR Am J Roentgenol 2017 Nov;209(5):1009-1014
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28898131
PMC ID: not available

Reconciling the Effects of Screening on Prostate Cancer Mortality in the ERSPC and PLCO Trials.

Tsodikov A,  Gulati R,  Heijnsdijk EAM,  Pinsky PF,  Moss SM,  Qiu S,  de Carvalho TM,  Hugosson J,  Berg CD,  Auvinen A,  Andriole GL,  Roobol MJ,  Crawford ED,  Nelen V,  Kwiatkowski M,  Zappa M,  Luján M,  Villers A,  Feuer EJ,  de Koning HJ,  Mariotto AB,  Etzioni R
Ann Intern Med 2017 Oct 3;167(7):449-455
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 28869989
PMC ID: PMC5734053

Interval lung cancer after a negative CT screening examination: CT findings and outcomes in National Lung Screening Trial participants.

Gierada DS,  Pinsky PF,  Duan F,  Garg K,  Hart EM,  Kazerooni EA,  Nath H,  Watts JR Jr,  Aberle DR
Eur Radiol 2017 Aug;27(8):3249-3256
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28050695
PMC ID: not available

Prostate Cancer Screening.

Pinsky PF,  Prorok PC,  Kramer BJ
N Engl J Med 2017 Jun 15;376(24):2402
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 28614680
PMC ID: not available

Incidental renal tumours on low-dose CT lung cancer screening exams.

Pinsky PF,  Dunn B,  Gierada D,  Nath PH,  Munden R,  Berland L,  Kramer BS
J Med Screen 2017 Jun;24(2):104-109
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director
PubMed ID: 28482765
PMC ID: not available

Data sharing in clinical trials: An experience with two large cancer screening trials.

Zhu CS,  Pinsky PF,  Moler JE,  Kukwa A,  Mabie J,  Rathmell JM,  Riley T,  Prorok PC,  Berg CD
PLoS Med 2017 May;14(5):e1002304
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director
PubMed ID: 28542201
PMC ID: PMC5441574

Flexible sigmoidoscopy screening: is once enough?

Pinsky PF
Lancet 2017 Apr 1;389(10076):1275-1277
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28236465
PMC ID: not available

Prostate Cancer Screening - A Perspective on the Current State of the Evidence.

Pinsky PF,  Prorok PC,  Kramer BS
N Engl J Med 2017 Mar 30;376(13):1285-1289
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 28355509
PMC ID: not available

Extended mortality results for prostate cancer screening in the PLCO trial with median follow-up of 15 years.

Pinsky PF,  Prorok PC,  Yu K,  Kramer BS,  Black A,  Gohagan JK,  Crawford ED,  Grubb RL,  Andriole GL
Cancer 2017 Feb 15;123(4):592-599
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 27911486
PMC ID: PMC5725951

Commentary on "Screening for lung cancer" by Sateia et al.

Pinsky PF
Semin Oncol 2017 Feb;44(1):83-84
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28395769
PMC ID: not available

Active follow-up versus passive linkage with cancer registries for case ascertainment in a cohort.

Pinsky PF,  Yu K,  Black A,  Huang WY,  Prorok PC
Cancer Epidemiol 2016 Dec;45:26-31
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 27687075
PMC ID: PMC5124516

The Prostate, Lung, Colorectal and Ovarian Cancer (PLCO) Screening Trial Pathology Tissue Resource.

Zhu CS,  Huang WY,  Pinsky PF,  Berg CD,  Sherman M,  Yu KJ,  Carrick DM,  Black A,  Hoover R,  Lenz P,  Williams C,  Hawkins L,  Chaloux M,  Yurgalevitch S,  Mathew S,  Miller A,  Olivo V,  Khan A,  Pretzel SM,  Multerer D,  Beckmann P,  Broski KG,  Freedman ND
Cancer Epidemiol Biomarkers Prev 2016 Dec;25(12):1635-1642
Major Program(s) or Research Group(s): Breast and Gynecologic CancerBiometryEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 27635065
PMC ID: PMC5135604

Population-Based Precision Cancer Screening: A Symposium on Evidence, Epidemiology, and Next Steps.

Marcus PM,  Pashayan N,  Church TR,  Doria-Rose VP,  Gould MK,  Hubbard RA,  Marrone M,  Miglioretti DL,  Pharoah PD,  Pinsky PF,  Rendle KA,  Robbins HA,  Roberts MC,  Rolland B,  Schiffman M,  Tiro JA,  Zauber AG,  Winn DM,  Khoury MJ
Cancer Epidemiol Biomarkers Prev 2016 Nov;25(11):1449-1455
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 27507769
PMC ID: PMC5165650

Extended mortality results for ovarian cancer screening in the PLCO trial with median 15years follow-up.

Pinsky PF,  Yu K,  Kramer BS,  Black A,  Buys SS,  Partridge E,  Gohagan J,  Berg CD,  Prorok PC
Gynecol Oncol 2016 Nov;143(2):270-275
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 27615399
PMC ID: PMC5077651

Colorectal Cancer Screening.

Pinsky PF,  Doroudi M
JAMA 2016 Oct 25;316(16):1715
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 27784086
PMC ID: not available

More on Reevaluating PSA Testing Rates in the PLCO Trial.

Pinsky P,  Prorok P
N Engl J Med 2016 Oct 13;375(15):1500-1501
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 27732807
PMC ID: not available

Lung cancer incidence and mortality in National Lung Screening Trial participants who underwent low-dose CT prevalence screening: a retrospective cohort analysis of a randomised, multicentre, diagnostic screening trial.

Patz EF Jr,  Greco E,  Gatsonis C,  Pinsky P,  Kramer BS,  Aberle DR
Lancet Oncol 2016 May;17(5):590-9
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  NCI Community Oncology Research Program
PubMed ID: 27009070
PMC ID: PMC5094059

Definition of Specificity in a Screening Trial.

Pinsky PF
J Clin Oncol 2016 Jan 10;34(2):198
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 26573070
PMC ID: not available

Lung Cancer Risk and Demographic Characteristics of Current 20-29 Pack-year Smokers: Implications for Screening.

Pinsky PF,  Kramer BS
J Natl Cancer Inst 2015 Nov;107(11)
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 26483244
PMC ID: PMC4849359

Incidence and mortality of colorectal cancer in individuals with a family history of colorectal cancer.

Schoen RE,  Razzak A,  Yu KJ,  Berndt SI,  Firl K,  Riley TL,  Pinsky PF
Gastroenterology 2015 Nov;149(6):1438-1445.e1
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 26255045
PMC ID: PMC4628587

The China Cancer Screening Trial Feasibility Study

Dai Min,  Hu Ping,  Shi Ju-Fang,  Ren Jian-Song,  Liao Xian-Zhen,  Du Ling-Bin,  Liu Yu-Qin,  Chen Zhao-Li,  Wu Ning,  Liu Qian,  Pinsky Paul,  Prorok Philip,  Fagerstrom Richard,  Taylor Martina,  Kramer Barnett,  He Jie
Lancet 2015 Oct;386(Suppl 1):35-35
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director
PubMed ID: not available
PMC ID: not available

Screening for cancer: lessons learned from the prostate, lung, colorectal, and ovarian cancer screening trial.

Grubb RL,  Pinsky P,  Prorok PC,  Andriole GL
Eur Urol 2015 Oct;68(4):545-6
Major Program(s) or Research Group(s): Biometry
PubMed ID: 25959167
PMC ID: not available

Occurrence of Distal Colorectal Neoplasia Among Whites and Blacks Following Negative Flexible Sigmoidoscopy: An Analysis of PLCO Trial.

Laiyemo AO,  Doubeni C,  Pinsky PF,  Doria-Rose VP,  Bresalier R,  Hickey T,  Riley T,  Church TR,  Weissfeld J,  Schoen RE,  Marcus PM,  Prorok PC
J Gen Intern Med 2015 Oct;30(10):1447-53
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 25835747
PMC ID: PMC4579215

Principles of Cancer Screening.

Pinsky PF
Surg Clin North Am 2015 Oct;95(5):953-66
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 26315516
PMC ID: PMC4555845

Lung cancer risk by years since quitting in 30+ pack year smokers.

Pinsky PF,  Zhu CS,  Kramer BS
J Med Screen 2015 Sep;22(3):151-7
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25926339
PMC ID: not available

Screening for Small Cell Lung Cancer: Analysis of the National Lung Cancer Screening Trial Data

Thomas Anish,  Szabo Eva,  Pinsky Paul
J Thorac Oncol 2015 Sep;10(9, Suppl 2):S221, Abstract ORAL25.01
Major Program(s) or Research Group(s): Early DetectionLung and Upper Aerodigestive Cancer
PubMed ID: not available
PMC ID: not available

Colorectal cancer incidence by age among patients undergoing surveillance colonoscopy.

Pinsky PF,  Schoen RE
JAMA Intern Med 2015 May;175(5):858-60
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25822077
PMC ID: not available

Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment.

Pinsky PF,  Gierada DS,  Black W,  Munden R,  Nath H,  Aberle D,  Kazerooni E
Ann Intern Med 2015 Apr 7;162(7):485-91
Major Program(s) or Research Group(s): Early DetectionNCI Community Oncology Research Program
PubMed ID: 25664444
PMC ID: PMC4705835

Cost-effectiveness of CT screening in the National Lung Screening Trial.

Pinsky PF
N Engl J Med 2015 Jan 22;372(4):387
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25607438
PMC ID: not available

PLCO: Evolution of an Epidemiologic Resource and Opportunities for Future Studies.

Black A,  Huang WY,  Wright P,  Riley T,  Mabie J,  Mathew S,  Ragard L,  Hermansen S,  Yu K,  Pinsky P,  Prorok PC,  Freedman ND,  Hoover RN
Rev Recent Clin Trials 2015;10(3):238-45
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 26435289
PMC ID: PMC6444921

Managing Multi-Center Recruitment in the PLCO Cancer Screening Trial.

Gohagan JK,  Broski K,  Gren LH,  Fouad MN,  Higgins D,  Lappe K,  Ogden S,  Shambaugh V,  Pinsky PF,  O'Brien B,  Yurgalevich S,  Riley T,  Wright P,  Prorok PC
Rev Recent Clin Trials 2015;10(3):187-93
Major Program(s) or Research Group(s): BiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 26435288
PMC ID: not available

Re: Is the area under an ROC curve a valid measure of the performance of a screening or diagnostic test?

Pinsky P
J Med Screen 2014 Dec;21(4):219
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25354869
PMC ID: not available

Short- and long-term lung cancer risk associated with noncalcified nodules observed on low-dose CT.

Pinsky PF,  Nath PH,  Gierada DS,  Sonavane S,  Szabo E
Cancer Prev Res (Phila) 2014 Dec;7(12):1179-85
Major Program(s) or Research Group(s): Early DetectionLung and Upper Aerodigestive Cancer
PubMed ID: 24755313
PMC ID: PMC4206664

Laboratory detective work identifies a mishandling problem in sample aliquoting.

Zhu C,  Pinsky P,  Huang WY,  Purdue M
Biopreserv Biobank 2014 Dec;12(6):430-2
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25496156
PMC ID: PMC4275770

National Lung Screening Trial findings by age: Medicare-eligible versus under-65 population.

Pinsky PF,  Gierada DS,  Hocking W,  Patz EF Jr,  Kramer BS
Ann Intern Med 2014 Nov 4;161(9):627-33
Major Program(s) or Research Group(s): Early DetectionNCI Community Oncology Research Program
PubMed ID: 25199624
PMC ID: PMC4505793

Sex steroid hormone metabolism in relation to risk of aggressive prostate cancer.

Black A,  Pinsky PF,  Grubb RL 3rd,  Falk RT,  Hsing AW,  Chu L,  Meyer T,  Veenstra TD,  Xu X,  Yu K,  Ziegler RG,  Brinton LA,  Hoover RN,  Cook MB
Cancer Epidemiol Biomarkers Prev 2014 Nov;23(11):2374-82
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 25178985
PMC ID: PMC4221438

Projected outcomes using different nodule sizes to define a positive CT lung cancer screening examination.

Gierada DS,  Pinsky P,  Nath H,  Chiles C,  Duan F,  Aberle DR
J Natl Cancer Inst 2014 Nov;106(11)
Major Program(s) or Research Group(s): Early DetectionNCI Community Oncology Research Program
PubMed ID: 25326638
PMC ID: PMC4207860

Re: prostate cancer mortality in areas with high and low prostate cancer incidence.

Pinsky PF
J Natl Cancer Inst 2014 Oct;106(10)
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 25269488
PMC ID: PMC4200068

Can symptomatic cancer be distinguished from screen detected cancer?

Schoen RE,  Pinsky PF
Gastroenterology 2014 Aug;147(2):545-6
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 24973674
PMC ID: not available

Estimating overdiagnosis in lung cancer screening--reply.

Patz EF Jr,  Pinsky P,  Kramer BS
JAMA Intern Med 2014 Jul;174(7):1198-9
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 25003885
PMC ID: not available

Comparative analysis of 5 lung cancer natural history and screening models that reproduce outcomes of the NLST and PLCO trials.

Meza R,  ten Haaf K,  Kong CY,  Erdogan A,  Black WC,  Tammemagi MC,  Choi SE,  Jeon J,  Han SS,  Munshi V,  van Rosmalen J,  Pinsky P,  McMahon PM,  de Koning HJ,  Feuer EJ,  Hazelton WD,  Plevritis SK
Cancer 2014 Jun 1;120(11):1713-24
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 24577803
PMC ID: PMC4031303

Benefits and harms of computed tomography lung cancer screening strategies: a comparative modeling study for the U.S. Preventive Services Task Force.

de Koning HJ,  Meza R,  Plevritis SK,  ten Haaf K,  Munshi VN,  Jeon J,  Erdogan SA,  Kong CY,  Han SS,  van Rosmalen J,  Choi SE,  Pinsky PF,  Berrington de Gonzalez A,  Berg CD,  Black WC,  Tammemägi MC,  Hazelton WD,  Feuer EJ,  McMahon PM
Ann Intern Med 2014 Mar 4;160(5):311-20
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 24379002
PMC ID: PMC4116741

Overdiagnosis in low-dose computed tomography screening for lung cancer.

Patz EF Jr,  Pinsky P,  Gatsonis C,  Sicks JD,  Kramer BS,  Tammemägi MC,  Chiles C,  Black WC,  Aberle DR,  NLST Overdiagnosis Manuscript Writing Team
JAMA Intern Med 2014 Feb 1;174(2):269-74
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 24322569
PMC ID: PMC4040004

Mortality and complications after prostate biopsy in the Prostate, Lung, Colorectal and Ovarian Cancer Screening (PLCO) trial.

Pinsky PF,  Parnes HL,  Andriole G
BJU Int 2014 Feb;113(2):254-9
Major Program(s) or Research Group(s): Early DetectionProstate and Urologic CancerProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 24053621
PMC ID: PMC3873374

Comparing benefits from many possible computed tomography lung cancer screening programs: extrapolating from the National Lung Screening Trial using comparative modeling.

McMahon PM,  Meza R,  Plevritis SK,  Black WC,  Tammemagi CM,  Erdogan A,  ten Haaf K,  Hazelton W,  Holford TR,  Jeon J,  Clarke L,  Kong CY,  Choi SE,  Munshi VN,  Han SS,  van Rosmalen J,  Pinsky PF,  Moolgavkar S,  de Koning HJ,  Feuer EJ
PLoS One 2014;9(6):e99978
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 24979231
PMC ID: PMC4076275

The prostate, lung, colorectal, and ovarian cancer screening trial and its associated research resource.

Zhu CS,  Pinsky PF,  Kramer BS,  Prorok PC,  Purdue MP,  Berg CD,  Gohagan JK
J Natl Cancer Inst 2013 Nov 20;105(22):1684-93
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 24115361
PMC ID: PMC3888207

The National Lung Screening Trial: results stratified by demographics, smoking history, and lung cancer histology.

Pinsky PF,  Church TR,  Izmirlian G,  Kramer BS
Cancer 2013 Nov 15;119(22):3976-83
Major Program(s) or Research Group(s): BiometryEarly Detection
PubMed ID: 24037918
PMC ID: PMC3936005

Diagnostic evaluation following a positive lung screening chest radiograph in the Prostate, Lung, Colorectal, Ovarian (PLCO) Cancer Screening Trial.

Hocking WG,  Tammemagi MC,  Commins J,  Oken MM,  Kvale PA,  Hu P,  Ragard LR,  Riley TL,  Pinsky P,  Beck TM,  Prorok PC
Lung Cancer 2013 Nov;82(2):238-44
Major Program(s) or Research Group(s): BiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 23993734
PMC ID: PMC3818308

Results of the two incidence screenings in the National Lung Screening Trial.

Aberle DR,  DeMello S,  Berg CD,  Black WC,  Brewer B,  Church TR,  Clingan KL,  Duan F,  Fagerstrom RM,  Gareen IF,  Gatsonis CA,  Gierada DS,  Jain A,  Jones GC,  Mahon I,  Marcus PM,  Rathmell JM,  Sicks J,  National Lung Screening Trial Research Team
N Engl J Med 2013 Sep 5;369(10):920-31
Major Program(s) or Research Group(s): BiometryNutritional Science
PubMed ID: 24004119
PMC ID: PMC4307922

National lung screening trial: variability in nodule detection rates in chest CT studies.

Pinsky PF,  Gierada DS,  Nath PH,  Kazerooni E,  Amorosa J
Radiology 2013 Sep;268(3):865-73
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 23592767
PMC ID: PMC3750416

Potential effect of the risk of ovarian cancer algorithm (ROCA) on the mortality outcome of the Prostate, Lung, Colorectal and Ovarian (PLCO) trial.

Pinsky PF,  Zhu C,  Skates SJ,  Black A,  Partridge E,  Buys SS,  Berg CD
Int J Cancer 2013 May 1;132(9):2127-33
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 23065684
PMC ID: not available

Projecting prostate cancer mortality in the PCPT and REDUCE chemoprevention trials.

Pinsky PF,  Black A,  Grubb R,  Crawford ED,  Andriole G,  Thompson I,  Parnes H
Cancer 2013 Feb 1;119(3):593-601
Major Program(s) or Research Group(s): Early Detection ;  Community Clinical Oncology Program ;  Community Oncology and Prevention TrialsProstate and Urologic CancerProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22893105
PMC ID: PMC3502695
Clinical Trials: Prostate Cancer Prevention Trial (PCPT)

Relationship between detection of adenomas by flexible sigmoidoscopy and interval distal colorectal cancer.

Rogal SS,  Pinsky PF,  Schoen RE
Clin Gastroenterol Hepatol 2013 Jan;11(1):73-8
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 22902761
PMC ID: PMC3525787

Factors associated with the risk of adenoma recurrence in distal and proximal colon.

Laiyemo AO,  Doubeni C,  Pinsky PF,  Doria-Rose VP,  Marcus PM,  Schoen RE,  Lanza E,  Cross AJ
Digestion 2013;87(3):141-6
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 23548665
PMC ID: PMC3755956

ROC curves for low-dose CT in the National Lung Screening Trial.

Pinsky PF,  Gierada DS,  Nath H,  Kazerooni EA,  Amorosa J
J Med Screen 2013;20(3):165-8
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 24009092
PMC ID: not available

Prostate cancer specific survival in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

Pinsky PF,  Black A,  Parnes HL,  Grubb R,  David Crawford E,  Miller A,  Reding D,  Andriole G
Cancer Epidemiol 2012 Dec;36(6):e401-6
Major Program(s) or Research Group(s): Early DetectionProstate and Urologic CancerProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 23000116
PMC ID: PMC3582194

Applying the National Lung Screening Trial eligibility criteria to the US population: what percent of the population and of incident lung cancers would be covered?

Pinsky PF,  Berg CD
J Med Screen 2012 Sep;19(3):154-6
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 23060474
PMC ID: not available

Factors associated with inadequate colorectal cancer screening with flexible sigmoidoscopy.

Laiyemo AO,  Doubeni C,  Pinsky PF,  Doria-Rose VP,  Sanderson AK 2nd,  Bresalier R,  Weissfeld J,  Schoen RE,  Marcus PM,  Prorok PC,  Berg CD
Cancer Epidemiol 2012 Aug;36(4):395-9
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22112544
PMC ID: PMC3288883

Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy.

Schoen RE,  Pinsky PF,  Weissfeld JL,  Yokochi LA,  Church T,  Laiyemo AO,  Bresalier R,  Andriole GL,  Buys SS,  Crawford ED,  Fouad MN,  Isaacs C,  Johnson CC,  Reding DJ,  O'Brien B,  Carrick DM,  Wright P,  Riley TL,  Purdue MP,  Izmirlian G,  Kramer BS,  Miller AB,  Gohagan JK,  Prorok PC,  Berg CD,  PLCO Project Team
N Engl J Med 2012 Jun 21;366(25):2345-57
Major Program(s) or Research Group(s): BiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22612596
PMC ID: PMC3641846

Enriched designs for assessing discriminatory performance--analysis of bias and variance.

Pinsky PF,  Gallas B
Stat Med 2012 Mar 15;31(6):501-15
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 22095795
PMC ID: not available

Colorectal cancers not detected by screening flexible sigmoidoscopy in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Schoen RE,  Pinsky PF,  Weissfeld JL,  Yokochi LA,  Church T,  Laiyemo AO,  Bresalier R,  Hickey T,  Riley T,  Prorok PC
Gastrointest Endosc 2012 Mar;75(3):612-20
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22341106
PMC ID: not available

Flexible sigmoidoscopy in the randomized prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial: added yield from a second screening examination.

Weissfeld JL,  Schoen RE,  Pinsky PF,  Bresalier RS,  Doria-Rose VP,  Laiyemo AO,  Church T,  Yokochi LA,  Yurgalevitch S,  Rathmell J,  Andriole GL,  Buys S,  Crawford ED,  Fouad M,  Isaacs C,  Lamerato L,  Reding D,  Prorok PC,  Berg CD,  PLCO Project Team
J Natl Cancer Inst 2012 Feb 22;104(4):280-9
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22298838
PMC ID: PMC3283538

Comparative effectiveness of digital versus film-screen mammography.

Pinsky PF
Ann Intern Med 2012 Feb 7;156(3):250; author reply 251
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 22312151
PMC ID: not available

Prostate cancer screening in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of follow-up.

Andriole GL,  Crawford ED,  Grubb RL 3rd,  Buys SS,  Chia D,  Church TR,  Fouad MN,  Isaacs C,  Kvale PA,  Reding DJ,  Weissfeld JL,  Yokochi LA,  O'Brien B,  Ragard LR,  Clapp JD,  Rathmell JM,  Riley TL,  Hsing AW,  Izmirlian G,  Pinsky PF,  Kramer BS,  Miller AB,  Gohagan JK,  Prorok PC,  PLCO Project Team
J Natl Cancer Inst 2012 Jan 18;104(2):125-32
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22228146
PMC ID: PMC3260132

Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized trial.

Oken MM,  Hocking WG,  Kvale PA,  Andriole GL,  Buys SS,  Church TR,  Crawford ED,  Fouad MN,  Isaacs C,  Reding DJ,  Weissfeld JL,  Yokochi LA,  O'Brien B,  Ragard LR,  Rathmell JM,  Riley TL,  Wright P,  Caparaso N,  Hu P,  Izmirlian G,  Pinsky PF,  Prorok PC,  Kramer BS,  Miller AB,  Gohagan JK,  Berg CD,  PLCO Project Team
JAMA 2011 Nov 2;306(17):1865-73
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 22031728
PMC ID: not available

Point estimates of number needed to treat/screen are insufficient without characterization of their uncertainty.

Pinsky PF
J Clin Oncol 2011 Aug 20;29(24):3336; author reply 3337
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 21768452
PMC ID: not available

Reduced lung-cancer mortality with low-dose computed tomographic screening.

National Lung Screening Trial Research Team,  Aberle DR,  Adams AM,  Berg CD,  Black WC,  Clapp JD,  Fagerstrom RM,  Gareen IF,  Gatsonis C,  Marcus PM,  Sicks JD
N Engl J Med 2011 Aug 4;365(5):395-409
Major Program(s) or Research Group(s): BiometryNutritional Science
PubMed ID: 21714641
PMC ID: PMC4356534

Likelihood of missed and recurrent adenomas in the proximal versus the distal colon.

Laiyemo AO,  Doubeni C,  Sanderson AK 2nd,  Pinsky PF,  Badurdeen DS,  Doria-Rose VP,  Marcus PM,  Schoen RE,  Lanza E,  Schatzkin A,  Cross AJ
Gastrointest Endosc 2011 Aug;74(2):253-61
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21549375
PMC ID: PMC3148340

Lung cancer risk prediction: Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial models and validation.

Tammemagi CM,  Pinsky PF,  Caporaso NE,  Kvale PA,  Hocking WG,  Church TR,  Riley TL,  Commins J,  Oken MM,  Berg CD,  Prorok PC
J Natl Cancer Inst 2011 Jul 6;103(13):1058-68
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21606442
PMC ID: PMC3131220

Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial.

Buys SS,  Partridge E,  Black A,  Johnson CC,  Lamerato L,  Isaacs C,  Reding DJ,  Greenlee RT,  Yokochi LA,  Kessel B,  Crawford ED,  Church TR,  Andriole GL,  Weissfeld JL,  Fouad MN,  Chia D,  O'Brien B,  Ragard LR,  Clapp JD,  Rathmell JM,  Riley TL,  Hartge P,  Pinsky PF,  Zhu CS,  Izmirlian G,  Kramer BS,  Miller AB,  Xu JL,  Prorok PC,  Gohagan JK,  Berg CD,  PLCO Project Team
JAMA 2011 Jun 8;305(22):2295-303
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21642681
PMC ID: not available

Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.

Cramer DW,  Bast RC Jr,  Berg CD,  Diamandis EP,  Godwin AK,  Hartge P,  Lokshin AE,  Lu KH,  McIntosh MW,  Mor G,  Patriotis C,  Pinsky PF,  Thornquist MD,  Scholler N,  Skates SJ,  Sluss PM,  Srivastava S,  Ward DC,  Zhang Z,  Zhu CS,  Urban N
Cancer Prev Res (Phila) 2011 Mar;4(3):365-74
Major Program(s) or Research Group(s): Early DetectionCancer BiomarkersProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21372036
PMC ID: PMC3085251

A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer.

Zhu CS,  Pinsky PF,  Cramer DW,  Ransohoff DF,  Hartge P,  Pfeiffer RM,  Urban N,  Mor G,  Bast RC Jr,  Moore LE,  Lokshin AE,  McIntosh MW,  Skates SJ,  Vitonis A,  Zhang Z,  Ward DC,  Symanowski JT,  Lomakin A,  Fung ET,  Sluss PM,  Scholler N,  Lu KH,  Marrangoni AM,  Patriotis C,  Srivastava S,  Buys SS,  Berg CD,  PLCO Project Team
Cancer Prev Res (Phila) 2011 Mar;4(3):375-83
Major Program(s) or Research Group(s): Early DetectionCancer BiomarkersBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21372037
PMC ID: PMC3057372

The National Lung Screening Trial: overview and study design.

National Lung Screening Trial Research Team,  Aberle DR,  Berg CD,  Black WC,  Church TR,  Fagerstrom RM,  Galen B,  Gareen IF,  Gatsonis C,  Goldin J,  Gohagan JK,  Hillman B,  Jaffe C,  Kramer BS,  Lynch D,  Marcus PM,  Schnall M,  Sullivan DC,  Sullivan D,  Zylak CJ
Radiology 2011 Jan;258(1):243-53
Major Program(s) or Research Group(s): BiometryNutritional Science
PubMed ID: 21045183
PMC ID: PMC3009383

Building multi-marker algorithms for disease prediction-the role of correlations among markers.

Pinsky PF,  Zhu CS
Biomark Insights 2011;6:83-93
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 21918599
PMC ID: PMC3169344

Baseline characteristics of participants in the randomized national lung screening trial.

National Lung Screening Trial Research Team,  Aberle DR,  Adams AM,  Berg CD,  Clapp JD,  Clingan KL,  Gareen IF,  Lynch DA,  Marcus PM,  Pinsky PF
J Natl Cancer Inst 2010 Dec 1;102(23):1771-9
Major Program(s) or Research Group(s): Biometry
PubMed ID: 21119104
PMC ID: PMC2994863

Assessing contamination and compliance in the prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

Pinsky PF,  Blacka A,  Kramer BS,  Miller A,  Prorok PC,  Berg C
Clin Trials 2010 Aug;7(4):303-11
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 20571134
PMC ID: not available

Transparency and reproducibility in data analysis: the Prostate Cancer Prevention Trial.

Baker SG,  Darke AK,  Pinsky P,  Parnes HL,  Kramer BS
Biostatistics 2010 Jul;11(3):413-8
Major Program(s) or Research Group(s): Prostate and Urologic CancerBiometry ;  Community Clinical Oncology Program ;  Community Oncology and Prevention Trials
PubMed ID: 20173101
PMC ID: PMC2883301
Clinical Trials: Prostate Cancer Prevention Trial (PCPT)

One year recurrence of aberrant crypt foci.

Pinsky PF,  Fleshman J,  Mutch M,  Rall C,  Charabaty A,  Seligson D,  Dry S,  Umar A,  Schoen RE
Cancer Prev Res (Phila) 2010 Jul;3(7):839-43
Major Program(s) or Research Group(s): Gastrointestinal and Other CancersEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 20570885
PMC ID: PMC2900400

Lung cancer screening in the randomized Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

Hocking WG,  Hu P,  Oken MM,  Winslow SD,  Kvale PA,  Prorok PC,  Ragard LR,  Commins J,  Lynch DA,  Andriole GL,  Buys SS,  Fouad MN,  Fuhrman CR,  Isaacs C,  Yokochi LA,  Riley TL,  Pinsky PF,  Gohagan JK,  Berg CD,  PLCO Project Team
J Natl Cancer Inst 2010 May 19;102(10):722-31
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 20442215
PMC ID: PMC2873186

Race and colorectal cancer disparities: health-care utilization vs different cancer susceptibilities.

Laiyemo AO,  Doubeni C,  Pinsky PF,  Doria-Rose VP,  Bresalier R,  Lamerato LE,  Crawford ED,  Kvale P,  Fouad M,  Hickey T,  Riley T,  Weissfeld J,  Schoen RE,  Marcus PM,  Prorok PC,  Berg CD
J Natl Cancer Inst 2010 Apr 21;102(8):538-46
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 20357245
PMC ID: PMC2857802

Ongoing colorectal cancer risk despite surveillance colonoscopy: the Polyp Prevention Trial Continued Follow-up Study.

Leung K,  Pinsky P,  Laiyemo AO,  Lanza E,  Schatzkin A,  Schoen RE
Gastrointest Endosc 2010 Jan;71(1):111-7
Major Program(s) or Research Group(s): Biometry
PubMed ID: 19647250
PMC ID: PMC3501210

Utilization of surveillance colonoscopy in community practice.

Schoen RE,  Pinsky PF,  Weissfeld JL,  Yokochi LA,  Reding DJ,  Hayes RB,  Church T,  Yurgalevich S,  Doria-Rose VP,  Hickey T,  Riley T,  Berg CD
Gastroenterology 2010 Jan;138(1):73-81
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19818779
PMC ID: PMC2813330

Reliability and accuracy of the endoscopic appearance in the identification of aberrant crypt foci.

Gupta AK,  Pinsky P,  Rall C,  Mutch M,  Dry S,  Seligson D,  Schoen RE
Gastrointest Endosc 2009 Aug;70(2):322-30
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19539919
PMC ID: PMC2727598

Prediction of true positive lung cancers in individuals with abnormal suspicious chest radiographs: a prostate, lung, colorectal, and ovarian cancer screening trial study.

Tammemagi MC,  Freedman MT,  Pinsky PF,  Oken MM,  Hu P,  Riley TL,  Ragard LR,  Berg CD,  Prorok PC
J Thorac Oncol 2009 Jun;4(6):710-21
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19404219
PMC ID: not available

Antioxidant supplementation and cancer prevention.

Pinsky PF
JAMA 2009 May 13;301(18):1878; author reply 1878
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 19436011
PMC ID: not available

Utilization and yield of surveillance colonoscopy in the continued follow-up study of the polyp prevention trial.

Laiyemo AO,  Pinsky PF,  Marcus PM,  Lanza E,  Cross AJ,  Schatzkin A,  Schoen RE
Clin Gastroenterol Hepatol 2009 May;7(5):562-7; quiz 497
Major Program(s) or Research Group(s): Biometry
PubMed ID: 19138760
PMC ID: PMC2701893

A multicenter study of prevalence and risk factors for aberrant crypt foci.

Mutch MG,  Schoen RE,  Fleshman JW,  Rall CJ,  Dry S,  Seligson D,  Charabaty A,  Chia D,  Umar A,  Viner J,  Hawk E,  Pinsky PF
Clin Gastroenterol Hepatol 2009 May;7(5):568-74
Major Program(s) or Research Group(s): Gastrointestinal and Other CancersEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19418605
PMC ID: not available

Mortality results from a randomized prostate-cancer screening trial.

Andriole GL,  Crawford ED,  Grubb RL 3rd,  Buys SS,  Chia D,  Church TR,  Fouad MN,  Gelmann EP,  Kvale PA,  Reding DJ,  Weissfeld JL,  Yokochi LA,  O'Brien B,  Clapp JD,  Rathmell JM,  Riley TL,  Hayes RB,  Kramer BS,  Izmirlian G,  Miller AB,  Pinsky PF,  Prorok PC,  Gohagan JK,  Berg CD,  PLCO Project Team
N Engl J Med 2009 Mar 26;360(13):1310-9
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening TrialChemopreventive Agent Development
PubMed ID: 19297565
PMC ID: PMC2944770

Serum prostate-specific antigen hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Grubb RL 3rd,  Black A,  Izmirlian G,  Hickey TP,  Pinsky PF,  Mabie JE,  Riley TL,  Ragard LR,  Prorok PC,  Berg CD,  Crawford ED,  Church TR,  Andriole GL Jr,  PLCO Project Team
Cancer Epidemiol Biomarkers Prev 2009 Mar;18(3):748-51
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19258472
PMC ID: not available

The yield of surveillance colonoscopy by adenoma history and time to examination.

Pinsky PF,  Schoen RE,  Weissfeld JL,  Church T,  Yokochi LA,  Doria-Rose VP,  Prorok P
Clin Gastroenterol Hepatol 2009 Jan;7(1):86-92
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 18829395
PMC ID: not available

Five-year risk of colorectal neoplasia after negative colonoscopy.

Schoen RE,  Pinsky PF
N Engl J Med 2008 Dec 11;359(24):2611; author reply 2612
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 19073983
PMC ID: not available

Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: update on findings from the initial four rounds of screening in a randomized trial.

Grubb RL 3rd,  Pinsky PF,  Greenlee RT,  Izmirlian G,  Miller AB,  Hickey TP,  Riley TL,  Mabie JE,  Levin DL,  Chia D,  Kramer BS,  Reding DJ,  Church TR,  Yokochi LA,  Kvale PA,  Weissfeld JL,  Urban DA,  Buys SS,  Gelmann EP,  Ragard LR,  Crawford ED,  Prorok PC,  Gohagan JK,  Berg CD,  Andriole GL
BJU Int 2008 Dec;102(11):1524-30
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19035857
PMC ID: not available

Lung cancer risk following detection of pulmonary scarring by chest radiography in the prostate, lung, colorectal, and ovarian cancer screening trial.

Yu YY,  Pinsky PF,  Caporaso NE,  Chatterjee N,  Baumgarten M,  Langenberg P,  Furuno JP,  Lan Q,  Engels EA
Arch Intern Med 2008 Nov 24;168(21):2326-32; discussion 2332
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 19029496
PMC ID: PMC2866505

Estimating rates of true high-grade disease in the prostate cancer prevention trial.

Pinsky P,  Parnes H,  Ford L
Cancer Prev Res (Phila) 2008 Aug;1(3):182-6
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate and Urologic CancerCommunity Oncology and Prevention Trials ;  Community Clinical Oncology Program
PubMed ID: 19138954
PMC ID: not available

The natural history of aberrant crypt foci.

Schoen RE,  Mutch M,  Rall C,  Dry SM,  Seligson D,  Umar A,  Pinsky P
Gastrointest Endosc 2008 Jun;67(7):1097-102
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 18178205
PMC ID: not available

Enrollment of racial and ethnic minorities in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.

Pinsky PF,  Ford M,  Gamito E,  Higgins D,  Jenkins V,  Lamerato L,  Tenorio S,  Marcus PM,  Gohagan JK
J Natl Med Assoc 2008 Mar;100(3):291-8
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 18390022
PMC ID: not available

Claims of sex-gene interactions.

Pinsky PF
JAMA 2007 Dec 19;298(23):2741-2; author reply 2742
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 18165666
PMC ID: not available

Prostate-specific antigen velocity and prostate cancer gleason grade and stage.

Pinsky PF,  Andriole G,  Crawford ED,  Chia D,  Kramer BS,  Grubb R,  Greenlee R,  Gohagan JK
Cancer 2007 Apr 15;109(8):1689-95
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 17330856
PMC ID: not available

Evidence of a healthy volunteer effect in the prostate, lung, colorectal, and ovarian cancer screening trial.

Pinsky PF,  Miller A,  Kramer BS,  Church T,  Reding D,  Prorok P,  Gelmann E,  Schoen RE,  Buys S,  Hayes RB,  Berg CD
Am J Epidemiol 2007 Apr 15;165(8):874-81
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 17244633
PMC ID: not available

Repeat prostate biopsy in the prostate, lung, colorectal and ovarian cancer screening trial.

Pinsky PF,  Crawford ED,  Kramer BS,  Andriole GL,  Gelmann EP,  Grubb R,  Greenlee R,  Gohagan JK
BJU Int 2007 Apr;99(4):775-9
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 17223921
PMC ID: not available

Yield of advanced adenoma and cancer based on polyp size detected at screening flexible sigmoidoscopy.

Schoen RE,  Weissfeld JL,  Pinsky PF,  Riley T
Gastroenterology 2006 Dec;131(6):1683-9
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 17188959
PMC ID: not available

Racial and ethnic differences in lung cancer incidence: how much is explained by differences in smoking patterns? (United States).

Pinsky PF
Cancer Causes Control 2006 Oct;17(8):1017-24
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 16933052
PMC ID: not available

Abnormalities on chest radiograph reported in subjects in a cancer screening trial.

Pinsky PF,  Freedman M,  Kvale P,  Oken M,  Caporaso N,  Gohagan J
Chest 2006 Sep;130(3):688-93
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16963664
PMC ID: not available

Prostate volume and prostate-specific antigen levels in men enrolled in a large screening trial.

Pinsky PF,  Kramer BS,  Crawford ED,  Grubb RL,  Urban DA,  Andriole GL,  Chia D,  Levin DL,  Gohagan JK
Urology 2006 Aug;68(2):352-6
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16904451
PMC ID: not available

Prostate specific antigen changes as related to the initial prostate specific antigen: data from the prostate, lung, colorectal and ovarian cancer screening trial.

Crawford ED,  Pinsky PF,  Chia D,  Kramer BS,  Fagerstrom RM,  Andriole G,  Reding D,  Gelmann EP,  Levin DL,  Gohagan JK
J Urol 2006 Apr;175(4):1286-90; discussion 1290
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16515981
PMC ID: not available

Modeling the effect of a preventive intervention on the natural history of cancer: application to the prostate cancer prevention trial

Pinsky P,  Etzioni R,  Howlader N,  Goodman P,  Thompson. IM
International Journal of Biostatistics 2006;2(1)
Major Program(s) or Research Group(s): Community Clinical Oncology Program ;  Community Oncology and Prevention TrialsProstate and Urologic Cancer
PubMed ID: not available
PMC ID: not available
Clinical Trials: Prostate Cancer Prevention Trial (PCPT)

Meat, meat cooking methods and preservation, and risk for colorectal adenoma.

Sinha R,  Peters U,  Cross AJ,  Kulldorff M,  Weissfeld JL,  Pinsky PF,  Rothman N,  Hayes RB
Cancer Res 2005 Sep 1;65(17):8034-41
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16140978
PMC ID: not available

Variability in flexible sigmoidoscopy performance among examiners in a screening trial.

Pinsky PF,  Schoen RE,  Weissfeld JL,  Kramer B,  Hayes RB,  Yokochi L,  PLCO Project Team
Clin Gastroenterol Hepatol 2005 Aug;3(8):792-7
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16234008
PMC ID: not available

Flexible sigmoidoscopy in the PLCO cancer screening trial: results from the baseline screening examination of a randomized trial.

Weissfeld JL,  Schoen RE,  Pinsky PF,  Bresalier RS,  Church T,  Yurgalevitch S,  Austin JH,  Prorok PC,  Gohagan JK,  PLCO Project Team
J Natl Cancer Inst 2005 Jul 6;97(13):989-97
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 15998952
PMC ID: not available

GSTM1, GSTT1, and GSTP1 polymorphisms and risk of advanced colorectal adenoma.

Moore LE,  Huang WY,  Chatterjee N,  Gunter M,  Chanock S,  Yeager M,  Welch B,  Pinsky P,  Weissfeld J,  Hayes RB
Cancer Epidemiol Biomarkers Prev 2005 Jul;14(7):1823-7
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 16030123
PMC ID: not available

Prostate Cancer Screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized trial.

Andriole GL,  Levin DL,  Crawford ED,  Gelmann EP,  Pinsky PF,  Chia D,  Kramer BS,  Reding D,  Church TR,  Grubb RL,  Izmirlian G,  Ragard LR,  Clapp JD,  Prorok PC,  Gohagan JK,  PLCO Project Team
J Natl Cancer Inst 2005 Mar 16;97(6):433-8
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 15770007
PMC ID: not available

Prostate biopsy following a positive screen in the prostate, lung, colorectal and ovarian cancer screening trial.

Pinsky PF,  Andriole GL,  Kramer BS,  Hayes RB,  Prorok PC,  Gohagan JK,  Prostate, Lung, Colorectal and Ovarian Project Team
J Urol 2005 Mar;173(3):746-1
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 15711261
PMC ID: not available

Diagnostic procedures after a positive spiral computed tomography lung carcinoma screen.

Pinsky PF,  Marcus PM,  Kramer BS,  Freedman M,  Nath H,  Kvale P,  Reding D
Cancer 2005 Jan 1;103(1):157-63
Major Program(s) or Research Group(s): Biometry
PubMed ID: 15529306
PMC ID: not available

Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer.

Gohagan JK,  Marcus PM,  Fagerstrom RM,  Pinsky PF,  Kramer BS,  Prorok PC,  Ascher S,  Bailey W,  Brewer B,  Church T,  Engelhard D,  Ford M,  Fouad M,  Freedman M,  Gelmann E,  Gierada D,  Hocking W,  Inampudi S,  Irons B,  Johnson CC,  Jones A,  Kucera G,  Kvale P,  Lappe K,  Manor W,  Moore A,  Nath H,  Neff S,  Oken M,  Plunkett M,  Price H,  Reding D,  Riley T,  Schwartz M,  Spizarny D,  Yoffie R,  Zylak C,  LUNG SCREENING STUDY RESEARCH GROUP
Lung Cancer 2005 Jan;47(1):9-15
Major Program(s) or Research Group(s): Biometry
PubMed ID: 15603850
PMC ID: not available

Screening for lung cancer.

Gohagan JK,  Marcus PM,  Fagerstrom RM,  Black WC,  Kramer BS,  Pinsky PF,  Prorok PC
2005
Gibson PG,  Abramson M,  Wood-Baker R,  Volmink J,  Hensley M,  Costabel U
Evidence-Based Respiratory Medicine.
ISBN: not available
Major Program(s) or Research Group(s): Biometry

Results of a randomized controlled trail of prostate cancer screening.

Pinsky PF
Prostate 2004 Dec 1;61(4):371
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 15503321
PMC ID: not available

Inter-rater agreement on chromosome 5 breakage in FISH-based mutagen sensitivity assays (MSAs).

Barker PE,  Wang W,  Wagner PD,  Pinsky P
Mutat Res 2004 Aug 8;562(1-2):133-42
Major Program(s) or Research Group(s): Cancer Biomarkers
PubMed ID: 15279836
PMC ID: not available

Baseline findings of a randomized feasibility trial of lung cancer screening with spiral CT scan vs chest radiograph: the Lung Screening Study of the National Cancer Institute.

Gohagan J,  Marcus P,  Fagerstrom R,  Pinsky P,  Kramer B,  Prorok P,  Writing Committee, Lung Screening Study Research Group
Chest 2004 Jul;126(1):114-21
Major Program(s) or Research Group(s): Biometry
PubMed ID: 15249451
PMC ID: not available

Circulating vitamin D metabolites, polymorphism in vitamin D receptor, and colorectal adenoma risk.

Peters U,  Hayes RB,  Chatterjee N,  Shao W,  Schoen RE,  Pinsky P,  Hollis BW,  McGlynn KA,  Prostate, Lung, Colorectal and Ovarian Cancer Screening Project Team
Cancer Epidemiol Biomarkers Prev 2004 Apr;13(4):546-52
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 15066918
PMC ID: not available

An early- and late-stage convolution model for disease natural history.

Pinsky PF
Biometrics 2004 Mar;60(1):191-8
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 15032789
PMC ID: not available

The Lung Screening Study: The National Cancer Institute's Randomized Feasibility Study of Spiral CT versus Chest X-ray in Lung Cancer Screening.

Kvale PA,  Gohagan J,  Marcus P,  Fagerstrom R,  Pinsky P,  Kramer B,  Prorok P
Chest 2003 Oct 28;124(4):118S
Major Program(s) or Research Group(s): Biometry
PubMed ID: not available
PMC ID: not available

Results of repeat sigmoidoscopy 3 years after a negative examination.

Schoen RE,  Pinsky PF,  Weissfeld JL,  Bresalier RS,  Church T,  Prorok P,  Gohagan JK,  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Group
JAMA 2003 Jul 2;290(1):41-8
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 12837710
PMC ID: not available

Reported family history of cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.

Pinsky PF,  Kramer BS,  Reding D,  Buys S,  PLCO Project Team
Am J Epidemiol 2003 May 1;157(9):792-9
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 12727673
PMC ID: not available

Predictors of advanced proximal neoplasia in persons with abnormal screening flexible sigmoidoscopy.

Pinsky PF,  Schoen RE,  Weissfeld JL,  Bresalier RS,  Hayes RB,  Gohagan JK
Clin Gastroenterol Hepatol 2003 Mar;1(2):103-10
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 15017502
PMC ID: not available

Screening for lung cancer.

Gohagan JK,  Marcus PM,  Fagerstrom RM,  Black WC,  Kramer BS,  Pinsky PF,  Prorok PC
2003
Williams C
Evidence-Based Oncology.
ISBN: not available
Major Program(s) or Research Group(s): Biometry

Relationship of demographic and clinical factors to free and total prostate-specific antigen.

Gelmann EP,  Chia D,  Pinsky PF,  Andriole GL,  Crawford ED,  Reding D,  Hayes RB,  Kramer BS,  Woodrum DL,  Gohagan JK,  Levin DL,  PLCO Screening Trial Investigators
Urology 2001 Oct;58(4):561-6
Major Program(s) or Research Group(s): Early DetectionBiometryProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 11597539
PMC ID: not available

A proposed design and analysis for comparing digital and analog mammography: Special receiver operating characteristic methods for cancer screening.

Baker SG,  Pinsky P
J Am Stat Assoc 2001 Jun;96(454):421-428
Major Program(s) or Research Group(s): Biometry
PubMed ID: not available
PMC ID: not available

Estimation and prediction for cancer screening models using deconvolution and smoothing.

Pinsky PF
Biometrics 2001 Jun;57(2):389-95
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 11414561
PMC ID: not available