Publication Results

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Examining the relationship between diabetes and prostate cancer through changes in screening guidelines.

Miller EA,  Pinsky PF
Cancer Causes Control 2020 Dec;31(12):1105-1113
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32970300
PMC ID: not available

Contribution of Surveillance Colonoscopy to Colorectal Cancer Prevention.

Pinsky PF,  Schoen RE
Clin Gastroenterol Hepatol 2020 Dec;18(13):2937-2944.e1
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32017987
PMC ID: PMC7549191 [available on December 01, 2021]

Artificial Intelligence and Data Mining to Assess Lung Cancer Risk: Challenges and Opportunities.

Pinsky P
Ann Intern Med 2020 Nov 3;173(9):760-761
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32866415
PMC ID: not available

Aspirin use and ovarian cancer risk using extended follow-up of the PLCO Cancer Screening Trial.

Hurwitz LM,  Pinsky PF,  Huang WY,  Freedman ND,  Trabert B
Gynecol Oncol 2020 Nov;159(2):522-526
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 32919779
PMC ID: PMC7584756 [available on November 01, 2021]

Breast Cancer Screening Trials: Endpoints and Over-diagnosis.

Jatoi I,  Pinsky PF
J Natl Cancer Inst 2020 Sep 8
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32898241
PMC ID: not available

Survival Following Detection of Stage I Lung Cancer by Screening in the National Lung Screening Trial.

Gierada DS,  Pinsky PF
Chest 2020 Aug 19
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32822676
PMC ID: not available

Breast cancer risk prediction models and subsequent tumor characteristics.

Miller EA,  Pinsky PF,  Heckman-Stoddard BM,  Minasian LM
Breast Cancer 2020 Jul;27(4):662-669
Major Program(s) or Research Group(s): Breast and Gynecologic CancerEarly Detection ;  Office of the Director
PubMed ID: 32056079
PMC ID: not available

Use of finasteride in the Prostate, Lung, Colorectal and Ovarian Cancer Prevention (PLCO) Trial cohort: Effects of sociodemographic factors and a black box warning

Johnson Jarrett A.,  Pinsky Paul F.
Cancer Epidemiol Biomarkers Prev 2020 Jun;29(6, Suppl 1):Abstract A071
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: not available
PMC ID: not available

Other- and all-cause Mortality among women with breast cancer.

Pierre-Victor D,  Pinsky PF,  McCaskill-Stevens W
Cancer Epidemiol 2020 Apr;65:101694
Major Program(s) or Research Group(s): Community Oncology and Prevention TrialsEarly Detection
PubMed ID: 32135504
PMC ID: not available

Low-Dose CT Screening for Lung Cancer: Evidence from 2 Decades of Study.

Gierada DS,  Black WC,  Chiles C,  Pinsky PF,  Yankelevitz DF
Radiol Imaging Cancer 2020 Mar 27;2(2):e190058
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32300760
PMC ID: PMC7135238

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis.

Ahdoot M,  Wilbur AR,  Reese SE,  Lebastchi AH,  Mehralivand S,  Gomella PT,  Bloom J,  Gurram S,  Siddiqui M,  Pinsky P,  Parnes H,  Linehan WM,  Merino M,  Choyke PL,  Shih JH,  Turkbey B,  Wood BJ,  Pinto PA
N Engl J Med 2020 Mar 5;382(10):917-928
Major Program(s) or Research Group(s): Early DetectionProstate and Urologic Cancer
PubMed ID: 32130814
PMC ID: PMC7323919

Thyroid Incidentalomas in Association With Low-Dose Computed Tomography in the National Lung Screening Trial.

Loomans-Kropp HA,  Dunn BK,  Kramer BS,  Pinsky P
Am J Epidemiol 2020 Jan 31;189(1):27-33
Major Program(s) or Research Group(s): BiometryCancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 31595954
PMC ID: not available

Recommendations Related to Genetic Testing for Breast Cancer.

Pinsky PF
JAMA 2020 Jan 14;323(2):187-188
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 31935023
PMC ID: not available

Long-term cancer risk associated with lung nodules observed on low-dose screening CT scans.

Pinsky P,  Gierada DS
Lung Cancer 2020 Jan;139:179-184
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 31812129
PMC ID: not available

Breast Cancer Characteristics and Survival among Users versus Nonusers of Raloxifene.

Pinsky PF,  Miller EA,  Heckman-Stoddard BM,  Minasian L
Cancer Prev Res (Phila) 2020 Jan;13(1):83-90
Major Program(s) or Research Group(s): Breast and Gynecologic CancerEarly Detection ;  Office of the Director
PubMed ID: 31796465
PMC ID: not available

Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment.

Muniraj N,  Siddharth S,  Shriver M,  Nagalingam A,  Parida S,  Woo J,  Elsey J,  Gabrielson K,  Gabrielson E,  Arbiser JL,  Saxena NK,  Sharma D
Cell Death Discov 2020;6:81
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 32963809
PMC ID: PMC7475061

Association of Aspirin Use With Mortality Risk Among Older Adult Participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Loomans-Kropp HA,  Pinsky P,  Cao Y,  Chan AT,  Umar A
JAMA Netw Open 2019 Dec 2;2(12):e1916729
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionGastrointestinal and Other Cancers
PubMed ID: 31800071
PMC ID: PMC6902761

Healthcare Access, Utilization, and Preventive Health Behaviors by Eligibility for Lung Cancer Screening.

Miller EA,  Pinsky PF
J Cancer Educ 2019 Oct 26
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 31656025
PMC ID: not available

Results of the lung and colorectal cancer screening study in China: a feasibility, randomised controlled trial

Li Jiang,  Hu Ping,  Shi Jufang,  Taylor Martina,  Li Ni,  Ren Jiansong,  Chen Hongda,  Liao Xianzhen,  Liu Yuqin,  Du Lingbin,  Pinsky Paul,  Prorok Philip,  Fagerstrom Richard,  Kramer Barnett,  Dai Min,  He Jie
Lancet 2019 Oct;394(1 Suppl):21-21
Major Program(s) or Research Group(s): BiometryCancer BiomarkersEarly Detection ;  Office of the Director
PubMed ID: not available
PMC ID: not available

Metastatic prostate cancer at diagnosis and through progression in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Pinsky PF,  Black A,  Daugherty SE,  Hoover R,  Parnes H,  Smith ZL,  Eggener S,  Andriole GL,  Berndt SI
Cancer 2019 Sep 1;125(17):2965-2974
Major Program(s) or Research Group(s): Early DetectionProstate and Urologic Cancer
PubMed ID: 31067347
PMC ID: PMC6690759

Overall mortality in men and women in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.

Pinsky PF,  Miller EA,  Zhu CS,  Prorok PC
J Med Screen 2019 Sep;26(3):127-134
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director
PubMed ID: 30943843
PMC ID: not available

Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon Honokiol treatment

Muniraj Nethaji,  Shriver Marey,  Nagalingam Arumugam,  Siddharth Sumit,  Parida Sheetal,  Saxena Neeraj K.,  Sharma Dipali
Cancer Res 2019 Jul;79(13 Suppl):Abstract 4271
Major Program(s) or Research Group(s): Early Detection
PubMed ID: not available
PMC ID: not available

Impact of comorbidity and age on treatment choice among men with localized prostate cancer.

Pinsky Paul F.,  Pierre-Victor Dudith,  Martin Iman K.,  Miller Eric,  McCaskill-Stevens Worta J.,  Grubb Robert L.
J Clin Oncol 2019 May 20;37(15 Suppl):Abstract e16585
Major Program(s) or Research Group(s): Community Oncology and Prevention TrialsEarly Detection
PubMed ID: not available
PMC ID: not available

Extended follow-up for prostate cancer incidence and mortality among participants in the Prostate, Lung, Colorectal and Ovarian randomized cancer screening trial.

Pinsky PF,  Miller E,  Prorok P,  Grubb R,  Crawford ED,  Andriole G
BJU Int 2019 May;123(5):854-860
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30288918
PMC ID: PMC6450783

Lung Cancer Screening Benefits and Harms Stratified by Patient Risk: Information to Improve Patient Decision Aids.

Bellinger C,  Pinsky P,  Foley K,  Case D,  Dharod A,  Miller D
Ann Am Thorac Soc 2019 Apr;16(4):512-514
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30620619
PMC ID: PMC6943875

Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma.

Siddharth S,  Muniraj N,  Saxena NK,  Sharma D
Cancers (Basel) 2019 Mar 30;11(4)
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30934990
PMC ID: PMC6521104

Association of Nonadherence to Cancer Screening Examinations With Mortality From Unrelated Causes: A Secondary Analysis of the PLCO Cancer Screening Trial.

Pierre-Victor D,  Pinsky PF
JAMA Intern Med 2019 Feb 1;179(2):196-203
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30592477
PMC ID: PMC6439655

Correction to: The relationship between diabetes, prostate-specific antigen screening tests, and prostate cancer.

Miller EA,  Pinsky PF,  Pierre-Victor D
Cancer Causes Control 2019 Feb;30(2):215-216
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 30506128
PMC ID: not available

Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: long-term follow-up of the randomised US PLCO cancer screening trial.

Miller EA,  Pinsky PF,  Schoen RE,  Prorok PC,  Church TR
Lancet Gastroenterol Hepatol 2019 Feb;4(2):101-110
Major Program(s) or Research Group(s): Early Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30502933
PMC ID: PMC6335177

Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells.

Muniraj N,  Siddharth S,  Nagalingam A,  Walker A,  Woo J,  Gyorffy B,  Gabrielson E,  Saxena NK,  Sharma D
Carcinogenesis 2019 Jan 29
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30698683
PMC ID: not available

Characteristics and Outcomes of Small Cell Lung Cancer Detected by CT Screening.

Thomas A,  Pattanayak P,  Szabo E,  Pinsky P
Chest 2018 Dec;154(6):1284-1290
Major Program(s) or Research Group(s): Early DetectionLung and Upper Aerodigestive Cancer
PubMed ID: 30080997
PMC ID: PMC6335258

The relationship between diabetes, prostate-specific antigen screening tests, and prostate cancer.

Miller EA,  Pinsky PF,  Pierre-Victor D
Cancer Causes Control 2018 Oct;29(10):907-914
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 30094676
PMC ID: not available

Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening.

Pinsky PF,  Loberg M,  Senore C,  Wooldrage K,  Atkin W,  Bretthauer M,  Cross AJ,  Hoff G,  Holme O,  Kalager M,  Segnan N,  Schoen RE
Gastroenterology 2018 Oct;155(4):1059-1068.e2
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29935150
PMC ID: not available

Power of a Trial Investigating a Low-Intensity PSA-Based Screening Intervention.

Pinsky PF
JAMA 2018 Aug 14;320(6):600
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30120468
PMC ID: not available

Secondary prostate cancer screening outcomes by race in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Screening Trial.

Miller EA,  Pinsky PF,  Black A,  Andriole GL,  Pierre-Victor D
Prostate 2018 Aug;78(11):830-838
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29667217
PMC ID: not available

The IARC Perspective on Colorectal Cancer Screening.

Pinsky P,  Rabeneck L,  Lauby-Secretan B
N Engl J Med 2018 Jul 19;379(3):301-302
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30021099
PMC ID: not available

Lung Cancer Mortality in the Lung Screening Study Feasibility Trial.

Doroudi M,  Pinsky PF,  Marcus PM
JNCI Cancer Spectr 2018 Jul;2(3):pky042
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection
PubMed ID: 31360863
PMC ID: PMC6649695

Lung cancer screening with low-dose CT: a world-wide view.

Pinsky PF
Transl Lung Cancer Res 2018 Jun;7(3):234-242
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 30050762
PMC ID: PMC6037972

False-positive screens and lung cancer risk in the National Lung Screening Trial: Implications for shared decision-making.

Pinsky PF,  Bellinger CR,  Miller DP Jr
J Med Screen 2018 Jun;25(2):110-112
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28929865
PMC ID: not available

Use of raloxifene and tamoxifen by breast cancer risk level in a Medicare-eligible cohort.

Pinsky PF,  Miller E,  Heckman-Stoddard B,  Minasian L
Am J Obstet Gynecol 2018 Jun;218(6):606.e1-606.e9
Major Program(s) or Research Group(s): Breast and Gynecologic CancerEarly Detection ;  Office of the Director
PubMed ID: 29630889
PMC ID: PMC5970073

Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence.

Click B,  Pinsky PF,  Hickey T,  Doroudi M,  Schoen RE
JAMA 2018 May 15;319(19):2021-2031
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29800214
PMC ID: PMC6583246

Comment on "Systematic review and meta-analysis by Dube et al."

Pinsky PF
Am J Gastroenterol 2018 May;113(5):780-781
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29453379
PMC ID: not available

Muscle-strengthening and aerobic activities and mortality among 3+ year cancer survivors in the U.S.

Tarasenko YN,  Linder DF,  Miller EA
Cancer Causes Control 2018 May;29(4-5):475-484
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29511931
PMC ID: not available

Does the evidence support the implementation of lung cancer screening with low-dose computed tomography?

Pinsky PF
Expert Rev Respir Med 2018 Apr;12(4):257-260
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29338501
PMC ID: not available

The efficacy of prostate-specific antigen screening: Impact of key components in the ERSPC and PLCO trials.

de Koning HJ,  Gulati R,  Moss SM,  Hugosson J,  Pinsky PF,  Berg CD,  Auvinen A,  Andriole GL,  Roobol MJ,  Crawford ED,  Nelen V,  Kwiatkowski M,  Zappa M,  Luján M,  Villers A,  de Carvalho TM,  Feuer EJ,  Tsodikov A,  Mariotto AB,  Heijnsdijk EAM,  Etzioni R
Cancer 2018 Mar 15;124(6):1197-1206
Major Program(s) or Research Group(s): Early DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29211316
PMC ID: PMC5839977

Overall and Multiphasic Findings of the Prostate, Lung, Colorectal and Ovarian (PLCO) Randomized Cancer Screening Trial.

Prorok PC,  Wright P,  Riley TR,  Kramer BS,  Berg CD,  Gohagan JK
Rev Recent Clin Trials 2018;13(4):257-273
Major Program(s) or Research Group(s): BiometryEarly Detection ;  Office of the Director ;  Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 29629665
PMC ID: not available

Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.

Kuppusamy P,  Nagalingam A,  Muniraj N,  Saxena NK,  Sharma D
Sci Rep 2017 Dec 20;7(1):17943
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 29263422
PMC ID: PMC5738353

Early detection versus primary prevention in the PLCO flexible sigmoidoscopy screening trial: Which has the greatest impact on mortality?

Doroudi M,  Schoen RE,  Pinsky PF
Cancer 2017 Dec 15;123(24):4815-4822
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly DetectionProstate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PubMed ID: 28976536
PMC ID: PMC5716922

The bimanual ovarian palpation examination in the Prostate, Lung, Colorectal and Ovarian cancer screening trial: Performance and complications.

Doroudi M,  Kramer BS,  Pinsky PF
J Med Screen 2017 Dec;24(4):220-222
Major Program(s) or Research Group(s): Cancer Prevention Fellowship ProgramEarly Detection ;  Office of the Director
PubMed ID: 27903809
PMC ID: not available

The relationship of cancer characteristics and patient outcome with time to lung cancer diagnosis after an abnormal screening CT.

Sonavane SK,  Pinsky P,  Watts J Jr,  Gierada DS,  Munden R,  Singh SP,  Nath H
Eur Radiol 2017 Dec;27(12):5113-5118
Major Program(s) or Research Group(s): Early Detection
PubMed ID: 28616728
PMC ID: not available