Cancer prevention in the era of precision oncology.
Journal: Clin Pharmacol Ther
Date: 2017 May
Major Program(s) or Research Group(s): CPFP, LUACRG
PubMed ID: 28032900
PMC ID: not available
Abstract: Cancer is a highly heterogeneous disease, both between and within different target organs. Precision cancer prevention requires understanding the molecular pathways leading to cancer on a "per-person" level, identification of individuals most at risk for developing cancer, and tailoring interventions to accommodate pathogenesis, risk, and individual responses to interventions. This commentary will discuss how an investment in precision prevention research can accelerate cancer prevention agent development-the key to reducing cancer incidence and mortality.