Mouse models of triple negative [basal-like/claudin low] breast cancer.
Journal: Breast Dis
Major Program(s) or Research Group(s): CADRG
PubMed ID: 21965308
PMC ID: not available
Abstract: Triple negative breast cancer encompasses the molecular subtypes of basal-like and the more recently defined claudin-low group. In this review, we discuss the identification and characterization of mouse models that mimic these human subtypes. These mouse models serve as useful tools for the study of disease biology and represent a valuable resource for the evaluation of experimental therapeutics.