A simple packed bed device for antibody labelled rare cell capture from whole blood.

Author(s): Kralj JG,  Arya C,  Tona A,  Forbes TP,  Munson MS,  Sorbara L,  Srivastava S,  Forry SP

Journal: Lab Chip

Date: 2012 Dec 7

Major Program(s) or Research Group(s): CBRG

PubMed ID: 23079718

PMC ID: not available

Abstract: We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics. We characterized the capture of MCF-7 cells spiked into whole human blood using this system to demonstrate that enrichment and enumeration studies give results similar to in situ surface-modified devices while reducing fabrication and operation complexity.