Treatment of Radiation-Induced Cognitive Decline in Adult Brain Tumor Patients.

Author(s): Cramer CK,  Cummings TL,  Andrews RN,  Strowd R,  Rapp SR,  Shaw EG,  Chan MD,  Lesser GJ

Journal: Curr Treat Options Oncol

Date: 2019 Apr 8

Major Program(s) or Research Group(s): NCORP

PubMed ID: 30963289

PMC ID: PMC6594685

Abstract: OPINION STATEMENT: Patients with either primary or metastatic brain tumors quite often have cognitive impairment. Maintaining cognitive function is important to brain tumor patients and a decline in cognitive function is generally accompanied by a decline in functional independence and performance status. Cognitive decline can be a result of tumor progression, depression/anxiety, fatigue/sleep dysfunction, or the treatments they have received. It is our opinion that providers treating brain tumor patients should obtain pre-treatment and serial cognitive testing in their patients and offer mitigating and therapeutic interventions when appropriate. They should also support cognition-focused clinical trials.